The relationship of remnant cholesterol and abdominal obesity in children: A cross-sectional study

作者全名："Tong, Jishuang; Li, Xinggui; Liang, Xiaoyue; Tang, Fang; Ren, Yanling; Hao, Guang; Peng, Xin; Luo, Sunqing; Feng, Ye; Huang, Daochao; Zhao, Li; Liang, Xiaohua"

作者地址："[Tong, Jishuang; Liang, Xiaoyue; Tang, Fang; Ren, Yanling; Peng, Xin; Luo, Sunqing; Feng, Ye; Huang, Daochao; Zhao, Li; Liang, Xiaohua] Chongqing Med Univ, Childrens Hosp, Natl Clin Res Ctr Child Hlth & Disorders, Minist Educ Key Lab Child Dev & Disorders,China In, Chongqing, Peoples R China; [Tong, Jishuang; Li, Xinggui] Shimian Peoples Hosp, Yaan, Peoples R China; [Tang, Fang] Chongqing Med & Pharmaceut Coll, Chongqing, Peoples R China; [Hao, Guang] Jinan Univ, Sch Med, Dept Publ Hlth & Prevent Med, Guangzhou, Peoples R China"

通信作者："Liang, XH (通讯作者)，Chongqing Med Univ, Childrens Hosp, Natl Clin Res Ctr Child Hlth & Disorders, Minist Educ Key Lab Child Dev & Disorders,China In, Chongqing, Peoples R China."

来源：FRONTIERS IN CARDIOVASCULAR MEDICINE

ESI学科分类：　

WOS号：WOS:000838417700001

JCR分区：Q2

影响因子：3.6

年份：2022

卷号：9

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：abdominal obesity; children; remnant cholesterol; urban-rural area; waist-to-height ratio

摘要："BackgroundPrevious studies found that remnant cholesterol (RC) is a risk factor for cardiovascular diseases and childhood obesity is associated with cardiometabolic diseases. This study aimed to explore the relationship between RC and abdominal obesity in children. MethodsA total of 5,959 children, aged 6-12 years old, were selected from a cross-sectional study in urban-rural areas of Chongqing, China. RC was calculated by total cholesterol (TC)-high-density lipoprotein (HDL-C) cholesterol-low-density lipoprotein (LDL-C) cholesterol and was divided into four groups by quartiles (Q1-Q4). ResultsCompared to children with the lowest RC (Q1), children with higher RC had significantly higher odds of abdominal obesity (Q2: OR = 1.450, 95% CI: 1.131-1.859, p < 0.05; Q3: OR = 2.127, 95% CI: 1.632-2.772, p < 0.001; Q4: OR = 2.386, 95% CI: 1.819-3.130, p < 0.001). In the stratified analyses by urban-rural areas, the odds ratios were greater in rural areas (Q2: OR = 2.228, 95% CI: 1.572-3.160, p < 0.001; Q3: OR = 3.668, 95% CI: 2.191-6.140, p < 0.001; Q4: OR = 6.490, 95% CI: 2.271-18.551, p < 0.001) than in urban areas (Q2: OR = 1.644, 95% CI: 1.192-2.266, p < 0.05; Q3: OR = 2.266, 95% CI: 1.667-3.082, p < 0.001; Q4: OR = 2.711, 95% CI: 2.005-3.665, p < 0.001). ConclusionsOur study found that RC was positively correlated with abdominal obesity in children, and this association was higher for children living in rural areas."

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