Infiltration of laponite: An effective approach to improve the mechanical properties and thermostability of collagen hydrogel
作者全名："Li, Jiao; Tian, Zhenhua; Yang, Huan; Duan, Lian; Liu, Yunfei"
作者地址："[Li, Jiao; Liu, Yunfei] Chongqing Med Univ, Stomatol Hosp, Chongqing 401147, Peoples R China; [Li, Jiao; Liu, Yunfei] Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing, Peoples R China; [Li, Jiao; Liu, Yunfei] Chongqing Municipal Key Lab Oral Biomed Engn High, Chongqing, Peoples R China; [Tian, Zhenhua] Shaanxi Univ Sci & Technol, Coll Bioresources Chem & Mat Engn, Xian, Peoples R China; [Yang, Huan] Qilu Univ Technol, Shandong Prov Key Lab Mol Engn, Sch Chem & Pharmaceut Engn, Shandong Acad Sci, Jinan, Peoples R China; [Duan, Lian] Southwest Univ, State Key Lab Silkworm Genome Biol, Coll Sericulture Text & Biomass Sci, Chongqing 400715, Peoples R China"
通信作者："Liu, YF (通讯作者)，Chongqing Med Univ, Stomatol Hosp, Chongqing 401147, Peoples R China.; Duan, L (通讯作者)，Southwest Univ, State Key Lab Silkworm Genome Biol, Coll Sericulture Text & Biomass Sci, Chongqing 400715, Peoples R China."
来源：JOURNAL OF APPLIED POLYMER SCIENCE
ESI学科分类：CHEMISTRY
WOS号：WOS:000881690900001
JCR分区：Q2
影响因子：3
年份：2022
卷号：
期号：
开始页：
结束页：
文献类型：Article; Early Access
关键词：collagen; hydrogel; laponite; mechanical properties; thermostability
摘要："Rapid aggregate precipitation of collagen and laponite in solution restricted the development of corresponding hybrid materials. Herein, a facile method of immerging collagen hydrogel into laponite dispersion was adopted to prepare hybrid collagen/laponite hydrogel, avoiding the precipitation. Collagen hydrogel shrunk and water content decreased dramatically after laponite solution treatment. According to the images of Scanning electron microscopy and energy dispersive system, the uniformly dispersed laponite in collagen hydrogel was observed, demonstrating infiltration of laponite into collagen hydrogel. X-ray photoelectron spectroscopy results revealed that coordination bonds generated between magnesium in laponite and collagen. Thermogravimetric analysis and Differential scanning calorimetry results displayed thermal decomposition temperature of collagen hydrogel increased from 321 to 342 degrees C, and denaturation temperature rose from 43.8 to 50.8 degrees C after laponite infiltration. Rheological and compressive tests showed the elastic modulus, fracture stress, compressive modulus and rupture point of hydrogel treated by 10% laponite were 695.2 Pa, 253.3 kPa, 13.5 kPa and 76.7%, respectively, which were about 3.5, 5.5, 45.0, and 1.4 times larger than those of pristine collagen hydrogel. Besides, enzyme degraded rate of collagen was decelerated, and the hydrogel was still nontoxic with the infiltration of laponite. The promising data demonstrated infiltration of laponite was an effective way to fabricate collagen/laponite hybrid materials with desirable properties."
基金机构："National Natural Science Foundation of China [22008201, 21706151]; Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission [cstc2021jcyj-msxmX0240]; Natural Science Foundation of Shaanxi Provincial Department of Education [21JK0549]; Natural Science Foundation of Shandong Province [ZR2021QB054]"
基金资助正文："National Natural Science Foundation of China, Grant/Award Numbers: 22008201, 21706151; Natural Science Foundation of Shaanxi Provincial Department of Education, Grant/Award Number: 21JK0549; Natural Science Foundation of Shandong Province, Grant/Award Number: ZR2021QB054; Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission, Grant/Award Number: cstc2021jcyj-msxmX0240"
