95% effective volume of ropivacaine for ultrasound-guided supra-inguinal fascia iliaca compartment block

作者全名："Zhang, Can; Dai, Wei; He, Kaihua"

作者地址："[Zhang, Can; Dai, Wei; He, Kaihua] Chongqing Med Univ, Affiliated Hosp 1, Anesthesiol Dept, Chongqing, Peoples R China"

通信作者："He, KH (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Anesthesiol Dept, Chongqing, Peoples R China."

来源：BMC ANESTHESIOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000960894500003

JCR分区：Q2

影响因子：2.3

年份：2023

卷号：23

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Supra-inguinal fascia iliaca compartment block; 95% effective volume; Ultrasound; Ropivacaine; Biased-coin design

摘要："Background Hip arthroplasty is effective in treating hip diseases, such as osteoarthritis and hip fracture, but it often brings severe trauma and pain. In recent years, ultrasound-guided supra-inguinal fascia iliaca compartment block(S-FICB) has become a widely used nerve block method for analgesia in hip arthroplasty. Methods Fifty-three patients preparing for hip arthroplasty were prospectively enrolled. S-FICB was performed under ultrasound guidance, and inject 0.33% ropivacaine into the space. Using the biased-coin design (BCD) sequential allocation method. The initial volume of 0.33% ropivacaine was 30ml. In case of failure, the next patient received a higher volume (defined as the previous volume with an increment of 1.2 mL). If the previous patient had a successful block, the next patient was randomized to a lower volume (defined as the previous volume with a decrement of 1.2 mL), with a probability of b = 0.05, or the same volume, with a probability of 1 - b = 0.95. The study was stopped when 45 successful blocks were achieved. Results Forty-five patients (84.9%) were blocked successfully. The 95% effective volume (EV95) was 34.06ml (95%CI 33.35 similar to 36.28ml). There were 31 patients with non-fracture in this study. The quadriceps muscle strength decreased in only two patients. Moreover, they both received 34.8ml of ropivacaine for S-FICB. Twenty-two patients had hip fractures. There were 3 patients (14%) with failed blocks and 19 patients (86%) with successful blocks. However, all fracture patients experienced less pain after S-FICB. Conclusion EV95 of 0.33% ropivacaine for ultrasound-guided S-FICB was 34.06ml."

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