Non-invasive brain stimulation for limb motor function and daily living activity improvement in acute stroke: A meta-analysis
作者全名:"Chen, Yirong; Yang, Lining; Li, Xiaohong; Tang, Lu; Pi, Yan; Bai, Dingqun"
作者地址:"[Chen, Yirong; Yang, Lining; Li, Xiaohong; Tang, Lu; Pi, Yan; Bai, Dingqun] Chongqing Med Univ, Dept Rehabil, Affiliated Hosp 1, Chongqing 400016, Peoples R China; [Bai, Dingqun] Chongqing Med Univ, Dept Rehabil, Affiliated Hosp 1, Yuanjiagang St,Youyi Rd 1, Chongqing, Peoples R China"
通信作者:"Bai, DQ (通讯作者),Chongqing Med Univ, Dept Rehabil, Affiliated Hosp 1, Yuanjiagang St,Youyi Rd 1, Chongqing, Peoples R China."
来源:JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
ESI学科分类:NEUROSCIENCE & BEHAVIOR
WOS号:WOS:000964307100001
JCR分区:Q3
影响因子:2
年份:2023
卷号:32
期号:4
开始页:
结束页:
文献类型:Article
关键词:Acute stroke; Non-invasive brain stimulation; Hemiplegia; Limb motor dysfunction; Activity of daily living
摘要:"Objective: To evaluate the effect of non-invasive brain stimulation (NIBS) in improv-ing limb motor dysfunction and daily living activity during at the phase of acute stroke. Materials and Methods: Randomized controlled trials about the effect of NIBS on hemiparesis in acute stroke were retrieved from databases of China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), Wanfang Data, CBM, PubMed, Embase, Cochrane Library, and Web of Sci-ence from inception until January 3rd 2022. The quality of the trials was assessed, and the data were extracted according to the Cochrane Handbook for Systematic Reviews of Interventions. A statistical analysis was carried out using Review Man-ager 5.3 and STATA 14. The effect size was evaluated by using the weighed mean difference (WMD) and a 95% confidence interval (CI). The stability and sensitivity of the results and sources of heterogeneity were also analyzed. Results: 12 studies involving 639 patients were included. Our meta-analysis showed that NIBS could improve the Fugl-Meyer Assessment (weighed mean difference = 3.96, 95% confi-dence interval = 3.45 to 4.48) and Barthel Index (weighed mean difference = 12.29, 95% confidence interval = 4.93 to 19.66), while reducing the National Institutes of Health Stroke Scale (weighed mean difference =-2.37, 95% confidence interval =-3.43 to-1.31). Conclusion: NIBS is effective in improving paretic limb motor function and activities of daily living in patients during at the phase of acute stroke."
基金机构:"Program for Youth Innovation in Future Medicine, Chongqing Medical Univer- sity [W0076]; Chongqing Education Commis- sion, Chongqing University Innovation Research Group [CXQT21018]; Chongqing Natural Science Foundation [CSTB2022NSCQ-MSX0862]"
基金资助正文:"Funding: This work was supported by Program for Youth Innovation in Future Medicine, Chongqing Medical Univer- sity [grant number W0076] ; Chongqing Education Commis- sion, Chongqing University Innovation Research Group [grant number CXQT21018] and Chongqing Natural Science Foundation [grant number CSTB2022NSCQ-MSX0862] ."