Comparison of different noncontrast computed tomographic markers for predicting early perihematomal edema expansion in patients with intracerebral hemorrhage

作者全名："Li, Yu-Lun; Zheng, Yi-Neng; Zhang, Li-juan; Li, Zuo-Qiao; Deng, Lan; Lv, Xin-Ni; Li, Qi; Lv, Fa-Jin"

作者地址："[Li, Yu-Lun; Zheng, Yi-Neng; Zhang, Li-juan; Lv, Fa-Jin] Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, Chongqing 400016, Peoples R China; [Li, Zuo-Qiao; Deng, Lan; Lv, Xin-Ni; Li, Qi] Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing 400016, Peoples R China"

通信作者："Lv, FJ (通讯作者)，Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, Chongqing 400016, Peoples R China.; Li, Q (通讯作者)，Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing 400016, Peoples R China."

来源：JOURNAL OF CLINICAL NEUROSCIENCE

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:000966449500001

JCR分区：Q3

影响因子：1.9

年份：2023

卷号：112

期号：　

开始页：1

结束页：5

文献类型：Article

关键词：Brain Edema; Cerebral Hemorrhage; Tomography; X-Ray Computed

摘要："Objectives: Noncontrast computed tomography (NCCT) imaging markers are associated with early perihematomal edema (PHE) growth. The aim of this study was to compare the predictive value of different NCCT markers in predicting early PHE expansion.Methods: ICH patients who underwent baseline CT scan within 6 h of symptoms onset and follow-up CT scan within 36 h between July 2011 and March 2017 were included in this study. The predictive value of hypodensity, satellite sign, heterogeneous density, irregular shape, blend sign, black hole sign, island sign and expansion -prone hematoma for early perihematomal edema expansion were assessed, separately.Results: 214 patients were included in our final analysis. After adjusting for ICH characteristics, hypodensity, blend sign, island sign and expansion-prone hematoma are still predictors of early perihematomal edema expansion in multivariable logistics regression analysis (all P < 0.05). The area under the receiver operating characteristic (ROC) curve of expansion-prone hematoma was significantly larger than the area under the ROC curve of hypodensity, blend sign and island sign in predicting PHE expansion (P = 0.003, P < 0.001 and P = 0.002, respectively).Conclusion: Compared with single NCCT imaging markers, expansion-prone hematoma seems to be optimal predictor for early PHE expansion than any single NCCT imaging marker."

基金机构："National Natural Science Foundation of China [82071337]; National Key Research and Development Program of China [2018YFC1312200, 2018YFC1312203]; Chongqing High -end Young Investigator Project [2019GDRC005]"

基金资助正文："Funding Q. Li reports grants from the National Natural Science Foundation of China (No. 82071337) , the National Key Research and Development Program of China (Grant No. 2018YFC1312200, No. 2018YFC1312203) , Chongqing High -end Young Investigator Project (No. 2019GDRC005) ."