Predictive value of acoustic cardiography for post-PCI early ventricular remodeling in acute myocardial infarction

作者全名："Wang, Weiwei; Hao, Haizhen; Fan, Tingting; Yue, Jia; Wang, Mingyang; Chen, Moshui; Deng, Guolan; Si, Liangyi; Zhang, Fuwei"

作者地址："[Wang, Weiwei; Fan, Tingting; Yue, Jia; Si, Liangyi; Zhang, Fuwei] Chongqing Med Univ, Affiliated Hosp 3, Div Cardiol, Chongqing, Peoples R China; [Hao, Haizhen; Chen, Moshui] Cent South Univ, Haikou Peoples Hosp, Dept Neurol, Haikou, Peoples R China; [Wang, Mingyang] Peoples Hosp Jiangbei Dist, Dept Crit Care Med, Chongqing, Peoples R China; [Deng, Guolan] Chongqing Med Univ, Affiliated Hosp 1, Div Cardiol, Chongqing, Peoples R China"

通信作者："Si, LY; Zhang, FW (通讯作者)，Chongqing Med Univ, Affiliated Hosp 3, Div Cardiol, Chongqing, Peoples R China."

来源：SCIENTIFIC REPORTS

ESI学科分类：Multidisciplinary

WOS号：WOS:000984935100029

JCR分区：Q1

影响因子：3.8

年份：2023

卷号：13

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："Acoustic cardiography is a completely new technology, it has great advantages in the rapid diagnosis of cardiovascular diseases. The purpose of this study was to investigate the clinical value of the fourth heart sound (S4), cardiac systolic dysfunction index (SDI), and the cardiac cycle time-corrected electromechanical activation time (EMATc) in the prediction of post-percutaneous coronary intervention (PCI) early ventricular remodeling (EVR) in patients with acute myocardial infarction (AMI). We recruited 161 patients with AMI of 72-h post-PCI, including 44 EVR patients with left ventricular ejection fraction (LVEF) < 50% and 117 Non-EVR patients (normal left ventricular systolic function group, LVEF >= 50%). EMATc, S4, and SDI were independent risk factors for post-PCI early ventricular remodeling in patients with AMI [S4 (OR 2.860, 95% CI 1.297-6.306, p = 0.009), SDI (OR 4.068, 95% CI 1.800-9.194, p = 0.001), and EMATc (OR 1.928, 95% CI 1.420-2.619, p < 0.001)]. The area under the receiver operating characteristic curve for EMATc was 0.89, with an optimal cutoff point of 12.2, EMATc had a sensitivity of 80% and a specificity of 83%. By contrast, an optimal cutoff point of 100 pg/ml, Serum brain natriuretic peptide had a sensitivity of 46% and a specificity of 83%. Our findings suggest the predictive value of EMATc for the occurrence of EVR in these patients was also identified; EMATc may be a simple, quick, and effective way to diagnose EVR after AMI."

基金机构：Chongqing Medical University

基金资助正文："We gratefully thank the patients who participated in our study. We gratefully also thank Jose PA, Jian Yang, and other research staff of the Division of Cardiology, Third Affiliated Hospital of Chongqing Medical University and Haikou people's Hospital for their assistance; This study was supported by a research grant from the Chongqing Medical University."