Dual-energy CT of the pancreas: comparison between virtual non-contrast images and true non-contrast images in the detection of pancreatic lesion

作者全名："Liang, Hongwei; Du, Silin; Yan, Gaowu; Zhou, Yang; Yang, Tianyu; Zhang, Zhiwei; Luo, Chenyi; Liao, Hongfan; Li, Yongmei"

作者地址："[Liang, Hongwei; Du, Silin; Zhou, Yang; Zhang, Zhiwei; Luo, Chenyi; Liao, Hongfan; Li, Yongmei] Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China; [Yan, Gaowu] Suining Cent Hosp, Dept Radiol, Suining 629000, Peoples R China; [Yang, Tianyu] Chongqing Med Univ, Dept Nucl Med, Affiliated Hosp 1, Chongqing 400016, Peoples R China"

通信作者："Li, YM (通讯作者)，Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：ABDOMINAL RADIOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000990061000001

JCR分区：Q2

影响因子：2.3

年份：2023

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期号：　

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文献类型：Article; Early Access

关键词：Dual energy computed tomography; Pancreatic lesion; Virtual non-contrast images; True non-contrast images

摘要："PurposeTo evaluate the image quality and diagnostic performance for pancreatic lesion between true non-contrast (TNC) and virtual non-contrast (VNC) images obtained from the dual-energy computed tomography (DECT).MethodsOne hundred six patients with pancreatic mass underwent contrast-enhanced DECT examinations were retrospectively included in this study. VNC images of the abdomen were generated from late arterial (aVNC) and portal (pVNC) phases. For quantitative analysis, the attenuation differences and reproducibility of abdominal organs were compared between TNC and aVNC/pVNC measurements. Qualitatively image quality was assessed by two radiologists using a five-point scale, and they independently compared the detection accuracy of pancreatic lesions between TNC and aVNC/pVNC images. The volume CT dose index (CTDIvol) and size-specific dose estimates (SSDE) were recorded to evaluate the potential dose reduction when using VNC reconstruction to replace the unenhanced phase.ResultsA total of 78.38% (765/976) of the attenuation measurement pairs were reproducible between TNC and aVNC images, and 71.0% (693/976) between TNC and pVNC images. In triphasic examinations, a total of 108 pancreatic lesions were found in 106 patients, and no significant difference in detection accuracy was found between TNC and VNC images (p = 0.587-0.957). Qualitatively, image quality was rated diagnostic (score >= 3) in all the VNC images. Calculated CTDIvol and SSDE reduction of about 34% could be achieved by omitting the non-contrast phase.ConclusionVNC images of DECT provide diagnostic image quality and accurate pancreatic lesions detection, which are a promising alternative to unenhanced phase with a substantial reduction of radiation exposure in clinical routine."

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