The role of left ventricular hypertrophy measured by echocardiography in screening patients with ischaemia with non-obstructive coronary arteries: a cross-sectional study

作者全名："Yang, Hao; Teng, Hua; Luo, Peng; Fu, Ruqian; Wang, Xiaoting; Qin, Guang; Gao, Min; Ren, Jianli"

作者地址："[Yang, Hao; Teng, Hua; Luo, Peng; Fu, Ruqian; Wang, Xiaoting; Qin, Guang; Gao, Min; Ren, Jianli] Chongqing Med Univ, Affiliated Hosp 2, Dept Ultrasound, Chongqing 400010, Peoples R China"

通信作者："Ren, JL (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Ultrasound, Chongqing 400010, Peoples R China."

来源：INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000993906200002

JCR分区：Q3

影响因子：1.5

年份：2023

卷号：　

期号：　

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结束页：　

文献类型：Article; Early Access

关键词：Ischaemia with non-obstructive coronary arteries; Left ventricular hypertrophy; Left ventricular mass index; Echocardiography

摘要："Many patients with ischaemia with non-obstructive coronary arteries (INOCA) have a poor prognosis. This study aims to explore the diagnostic value of left ventricular hypertrophy (LVH)-related ultrasound parameters in INOCA patients. The study group consisted of 258 patients with INOCA in this retrospective cross-sectional study, and these patients were free of obstructive coronary artery disease, previous revascularization, atrial fibrillation, ejection fraction < 50%, major distortions of left ventricular geometry, suspected non-ischaemic causes. Control individuals were matched 1:1 with study group according to age, sex, cardiovascular risk factors, and time of hospital stay. According to left ventricular mass index (LVMI) and relative wall thickness, left ventricular geometry was composed of concentric hypertrophy, eccentric hypertrophy, concentric remodeling and normal geometry. LVH-related parameters, left ventricular geometry, demographic characteristics, laboratory parameters and other echocardiographic indicators were compared between the two groups. Subgroup analysis was performed based on sex. LVMI in the study group was higher than that in the control group (86.86 +/- 18.83 g/m(2) vs 82.25 +/- 14.29 g/m(2), P = 0.008). The ratio of LVH was higher in the study group (20.16% vs 10.85%, P = 0.006). After subgroup analysis based on sex, LVMI differences (85.77 +/- 18.30 g/m(2) vs 81.59 +/- 14.64 g/m(2), P = 0.014) and the ratio of LVH differences (25.00% vs 14.77%, P = 0.027) still existed in females between the two groups. There was no difference in the constituent ratio of left ventricular geometry between the two groups (P = 0.157). Sex-based subgroup analysis showed no difference in the constituent ratio of left ventricular geometry between the two groups in females (P = 0.242). The degree of LVH in the study group was higher than that in the control group, suggesting that LVH may play an important role in the occurrence and development of INOCA. Moreover, LVH-related ultrasound parameters may be of higher diagnostic value for female INOCA patients than for male INOCA patients."

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