"Comparison of Three Algorithms for Predicting Infarct Volume in Patients with Acute Ischemic Stroke by CT Perfusion Software: Bayesian, CSVD, and OSVD"

作者全名："Yao, Yunzhuo; Gu, Sirun; Liu, Jiayang; Li, Jing; Wu, Jiajing; Luo, Tianyou; Li, Yongmei; Ge, Bing; Wang, Jingjie"

作者地址："[Yao, Yunzhuo; Gu, Sirun; Liu, Jiayang; Li, Jing; Wu, Jiajing; Luo, Tianyou; Li, Yongmei; Wang, Jingjie] Chongqing Med Univ, Affiliated Hosp 1, Dept Radiol, 1 Youyi Rd, Chongqing 400016, Peoples R China; [Li, Jing] Cent Hosp Shaoyang, Med Imaging Ctr, Shaoyang 422000, Peoples R China; [Wu, Jiajing] NO 958th Hosp PLA Army, Chongqing 400020, Peoples R China; [Ge, Bing] Canon Med Syst Clin Sci Dept, 162 North Dist Rd, Chongqing 400016, Peoples R China"

通信作者："Wang, JJ (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Radiol, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：DIAGNOSTICS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000998207700001

JCR分区：Q1

影响因子：3

年份：2023

卷号：13

期号：10

开始页：　

结束页：　

文献类型：Article

关键词：bayesian; CT perfusion; infarct core; ischemic stroke; singular value decomposition

摘要："This study aimed to compare the performance of the Bayesian probabilistic method, circular Singular Value Decomposition (cSVD), and oscillation index Singular Value Decomposition (oSVD) algorithms in Olea Sphere for predicting infarct volume in patients with acute ischemic stroke (AIS). Eighty-seven patients suffering from AIS with large vessel occlusion were divided into improvement and progression groups. The improvement group included patients with successful recanalization (TICI 2b-3) after thrombectomy or whose clinical symptoms improved after thrombolysis. The progression group consisted of patients whose clinical symptoms did not improve or even got worse. The infarct core volume from the Olea Sphere software was used as the predicted infarct volume (PIV) in the improvement group, whereas the hypoperfusion volume was used as the PIV in the progression group. We defined predicted difference (PD) as PIV minus final infarct volume (FIV) measured at follow-up imaging. Differences among the three algorithms were assessed by the Friedman test. Spearman correlation analysis was used to verify the correlation between PIV and FIV. In addition, we performed a subgroup analysis of the progression group based on collateral circulation status. The median [interquartile range (IQR)] of the PD and Spearman correlation coefficients (SCCs) between PIV and FIV for the improvement group (n = 22) were: Bayesian = [6.99 (-14.72, 18.99), 0.500]; oSVD = [-12.74 (-41.06, -3.46), 0.423]; cSVD = [-15.38 (-38.92, -4.68), 0.586]. For the progression group (n = 65), the median (IQR) of PD and SCCs were: Bayesian = [1.00 (-34.07, 49.37), 0.748]; oSVD = [-0.17 (-53.42, 29.73), 0.712]; cSVD = [66.55 (7.94, 106.32), 0.674]. The Bayesian algorithm in the Olea Sphere software predicted infarct volumes with better accuracy and stability than the other two algorithms in both the progression and improvement groups."

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