A randomized controlled comparative study of different fluid exchange modes in urgent-start peritoneal dialysis in patients with end-stage renal disease: automated peritoneal dialysis combined with manual fluid exchange vs. manual fluid exchange alone

作者全名："Xia, Xiaoxiao; He, Xueqin; Pu, Li; Liu, Xia; Zhou, Xueli; Wu, Xiao Fang; Zang, Zhiyun; Li, Zi"

作者地址："[Xia, Xiaoxiao; He, Xueqin; Pu, Li; Liu, Xia; Zhou, Xueli; Wu, Xiao Fang; Zang, Zhiyun; Li, Zi] Sichuan Univ, West China Hosp, Dept Nephrol, Chengdu, Peoples R China; [He, Xueqin; Pu, Li; Liu, Xia; Zhou, Xueli] Sichuan Univ, West China Sch Nursing, West China Hosp, Chengdu, Peoples R China; [Wu, Xiao Fang] Chongqing Med Univ, Affiliated Hosp 3, Gener Hosp, Dept Nephrol, Chongqing, Peoples R China"

通信作者："Li, Z (通讯作者)，Sichuan Univ, West China Hosp, Dept Nephrol, Chengdu, Peoples R China."

来源：RENAL FAILURE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001005751000001

JCR分区：Q1

影响因子：3

年份：2023

卷号：45

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Automated peritoneal dialysis; manual fluid exchange peritoneal dialysis; urgent-start peritoneal dialysis; end-stage renal disease

摘要："During urgent-start peritoneal dialysis (USPD) in end-stage renal disease (ESRD) patients, both adequate dialysis and skill training for fluid exchange are essential. However, automated peritoneal dialysis (APD) alone or manual fluid exchange peritoneal dialysis (MPD) alone could meet the above demands. Therefore, our study combined APD with MPD (A-MPD), and compared A-MPD with MPD, aiming to find the most appropriate treatment mode. This was a single-center, prospective, randomized controlled study. All eligible patients were randomized into the MPD and A-MPD groups. All patients underwent a five-day USPD treatment 48 h after catheter implantation, and they were followed up for six months after discharge. Overall, 74 patients were enrolled in this study. Among these, 14 and 60 patients quit due to complications during USPD and completed the study (A-MPD = 31, MPD = 29), respectively. Compared with MPD, the A-MPD treatment mode had a better effect on removing serum creatinine, blood urea nitrogen, and potassium and improving serum carbon dioxide combining power levels; it had less time expenditure on the fluid exchange by nurses (p < 0.05). In addition, patients in the A-MPD group had higher scores on the skill tests than those in the MPD group (p = 0.002). However, no significant differences in short-term peritoneal dialysis (PD) complications, PD technical survival rate, or mortality were found between the two groups. Therefore, the A-MPD mode could be recommended as an adoptable and suitable PD modality for USPD in the future."

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