Intrarectal Foley catheter-assisted high-intensity focused ultrasound ablation for benign uterine diseases beyond the treatment region

作者全名："Liu, Wei; Kim, Tae-Hee; Huang, Lihui; Chen, Xing; Feng, Chunping; Liu, Ling; Zhang, Li; Zhang, Wen; Zhou, Kun; Gan, Xiuni"

作者地址："[Liu, Wei; Huang, Lihui; Chen, Xing; Feng, Chunping; Liu, Ling; Zhang, Li; Zhang, Wen; Zhou, Kun] Chongqing Med Univ, Affiliated Hosp 2, Clin Ctr Tumor Therapy, Chongqing, Peoples R China; [Kim, Tae-Hee] Seoul HIcare Clin, Seoul, South Korea; [Gan, Xiuni] Chongqing Med Univ, Affiliated Hosp 2, Nursing Dept, Chongqing, Peoples R China"

通信作者："Zhou, K (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Clin Ctr Tumor Therapy, Chongqing, Peoples R China."

来源：INTERNATIONAL JOURNAL OF HYPERTHERMIA

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001010183700001

JCR分区：Q2

影响因子：3

年份：2023

卷号：40

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Benign uterine disease; high-intensity focused ultrasound; intrarectal Foley catheter; feasibility analysis; safety

摘要："Objective To evaluate the feasibility of using an intrarectal Foley catheter during ultrasound-guided high-intensity focused ultrasound (US-HIFU) in patients with benign uterine diseases of the posterior wall beyond the HIFU therapeutic range. Methods Patients were treated with US-HIFU and lesion changes were monitored using contrast-enhanced MRI from June 2020 to September 2021. A Foley catheter was inserted into the rectum to facilitate a successful US-HIFU ablation. Complications and lesion responses were recorded during the treatment and follow-up. Results Thirteen patients with 14 lesions beyond the device's treatable area were enrolled. The average placement time and insertion depth of the intrarectal Foley catheter was 7.6 +/- 2.7 min and 23.2 +/- 7.6 cm, respectively. A median of 50 mL degassed water was injected into the Foley catheter balloon. All 14 lesions were successfully pushed into a treatable area and subjected to HIFU. The average treatment time, irradiation time, and total therapeutic energy of HIFU were 44.2 +/- 17.3 min, 394.4 +/- 295.7 s, and 73.3 +/- 46.6 kJ, respectively. The mean non-perfusion volume (NPV) in all treated lesions was 23.2 +/- 19.2 cm3, and the mean NPV ratio was 57.8 +/- 16.9%. Major complications were not observed. Conclusion Intrarectal Foley catheter-assisted US-HIFU is effective and safe. Its clinical application could benefit patients with benign uterine diseases outside the HIFU therapeutic range."

基金机构：Kuanren Talents Program of the Second Affiliated Hospital of Chongqing Medical University [KY2019G019]; Future Medical Youth Innovation Team Support Program Project of Chongqing Medical University [2021 W0061]

基金资助正文：This work was supported by the Kuanren Talents Program of the Second Affiliated Hospital of Chongqing Medical University [No: KY2019G019] and The Future Medical Youth Innovation Team Support Program Project of Chongqing Medical University [No: 2021 W0061].