"What contributes to the re-positive nucleic acid test results for the omicron variant of SARS-CoV-2 in the shelter cabin hospital in Shanghai, China?"

作者全名："Peng, Mei; Hu, Maozi; Peng, Xiaolu; Gong, Yuan; Qian, Keli; Li, Junnan; Zhao, Jinqiu; Li, Xiang; Huang, Jing; Zhang, Meng; Chai, Lili; Chen, Li; Zhang, Dan; Peng, Li"

作者地址："[Peng, Mei; Peng, Xiaolu; Peng, Li] Chongqing Med Univ, Affiliated Hosp 1, Dept Resp & Crit Care Med, Chongqing, Peoples R China; [Hu, Maozi] Jiulongpo Dist Hosp Chongqing, Gastroenterol Dept, Chongqing, Peoples R China; [Gong, Yuan] Jiulongpo Dist Hosp Chongqing, Crit Care Med Dept, Chongqing, Peoples R China; [Qian, Keli] Chongqing Med Univ, Affiliated Hosp 1, Dept Nosocomial Infect Control, Chongqing, Peoples R China; [Li, Junnan] Chongqing Med Univ, Affiliated Hosp 1, Dept Obstet & Fetal Med Unit, Chongqing, Peoples R China; [Zhao, Jinqiu] Chongqing Med Univ, Affiliated Hosp 1, Dept Infect Dis, Chongqing, Peoples R China; [Li, Xiang] Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiovasc Med, Chongqing, Peoples R China; [Huang, Jing] Chongqing Gen Hosp, Dept Resp Med, Chongqing, Peoples R China; [Zhang, Meng] Chongqing Gen Hosp, Dept Crit Care Med, Chongqing, Peoples R China; [Chai, Lili] Fifth Rehabil Hosp Shanghai, Infect Dept, Shanghai, Peoples R China; [Chen, Li] Chongqing Med Univ, Affiliated Hosp 1, Med Serv Div, Chongqing, Peoples R China; [Zhang, Dan] Chongqing Med Univ, Affiliated Hosp 1, Dept Crit Care Med, Chongqing, Peoples R China; [Peng, Li] Chongqing Med Univ, Affiliated Hosp 1, Dept Resp & Crit Care Med, 1 Youyi Rd, Chongqing, Peoples R China"

通信作者："Peng, L (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Resp & Crit Care Med, 1 Youyi Rd, Chongqing, Peoples R China."

来源：HELIYON

ESI学科分类：　

WOS号：WOS:001040756500001

JCR分区：Q1

影响因子：3.4

年份：2023

卷号：9

期号：5

开始页：　

结束页：　

文献类型：Article

关键词：COVID-19; Omicron variant; Re-positivity; Vaccination; Shelter cabin hospital; Nucleic acid test

摘要："Background: Despite the increasing reports of re-positive SARS-CoV-2 cases after recovery and discharge from hospitals, our knowledge remains very limited regarding the contributing factors of re-positivity and its roles in the transmission and epidemiology of the Omicron variant. Methods: In this retrospective study, re-positivity is defined as the positive nucleic acid result (Ct < 35) following two consecutive negative results during hospitalization. A total of 751 patients from Shanghai Shelter Cabin Hospital were enrolled and divided with a ratio of about 1:2 into the re-positivity group and the non-re-positivity group. Patients required three consecutive negative results daily as the de-isolation criterion. The follow-up time of discharged patients lasted five weeks. Univariate regression analysis was used to compare variables between the re-positivity and non-re-positivity groups, and the single re-positivity and multiple re-positivity groups, with P < 0.05 defined as the statistical significance of differences. Subsequently, variables with P < 0.2 were subjected to multivariate logistic regression analysis to investigate the odds ratio (OR) of repositivity and the influencing factors of re-positivity of the Omicron variant. Results: The re-positivity group had a higher proportion of males (68.1% vs 58.1%, p = 0.000), a higher education level (31.9% vs 12.7%, p = 0.007), a longer hospitalization duration (13 days vs 8 days, p = 0.000), and a higher Convidecia vaccination rate (6.0% vs 2.4%, p = 0.011). Further"

基金机构：　

基金资助正文：