Involvement in treatment decision-making and self-reported efficacy among patients with advanced colorectal cancer: a nationwide multi-center cross-sectional study

作者全名："Gu, Xiao-Fen; Xu, Hui-Fang; Liu, Yin; Li, Li; Yu, Yan-Qin; Zhang, Xi; Wang, Xiao-Hui; Wang, Wen-Jun; Du, Ling-Bin; Duan, Shuang-Xia; Cao, He-Lu; Zhao, Yu-Qian; Liu, Yun-Yong; Huang, Juan-Xiu; Cao, Ji; Fan, Yan-Ping; Feng, Chang-Yan; Lian, Xue-Mei; Du, Jing-Chang; Rezhake, Remila; Ma, Li; Qiao, You-Lin"

作者地址："[Gu, Xiao-Fen; Rezhake, Remila; Qiao, You-Lin] Xinjiang Med Univ, Affiliated Canc Hosp, Dept Student Affairs, Urumqi, Peoples R China; [Xu, Hui-Fang; Liu, Yin; Qiao, You-Lin] Zhengzhou Univ, Affiliated Canc Hosp, Dept Canc Epidemiol, Zhengzhou, Peoples R China; [Xu, Hui-Fang; Liu, Yin; Qiao, You-Lin] Henan Canc Hosp, Henan Engn Res Ctr Canc Prevent & Control, Henan Int Joint Lab Canc Prevent, Zhengzhou, Peoples R China; [Li, Li] Jinan Univ, Affiliated Hosp 1, Dept Clin Res, Guangzhou, Guangdong, Peoples R China; [Yu, Yan-Qin] Baotou Med Coll, Clin Epidemiol Res Ctr, Dept Publ Hlth & Prevent Med, Baotou, Peoples R China; [Zhang, Xi] Peking Univ, Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res, Beijing Off Canc Prevent & Control,Minist Educ Be, Beijing, Peoples R China; [Wang, Xiao-Hui] Gansu Prov Canc Hosp, Dept Publ Hlth, Lanzhou, Peoples R China; [Wang, Wen-Jun] Jining Med Univ, Sch Nursing, Jining, Peoples R China; [Du, Ling-Bin] Univ Chinese Acad Sci, Zhejiang Canc Hosp, Canc Hosp, Dept Canc Prevent, Hangzhou, Peoples R China; [Duan, Shuang-Xia; Cao, He-Lu] Xinxiang Cent Hosp, Dept Prevent Hlth, Xinxiang, Peoples R China; [Zhao, Yu-Qian] Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Ctr Canc Prevent Res, Sichuan Canc Ctr,Sch Med, Chengdu, Peoples R China; [Liu, Yun-Yong] China Med Univ, Liaoning Canc Hosp & Inst, Canc Hosp, Liaoning Off Canc Control & Res, Shenyang, Peoples R China; [Huang, Juan-Xiu] Wuzhou Red Cross Hosp, Dept Gastrodiges, Wuzhou, Peoples R China; [Cao, Ji] Guangxi Med Univ, Affiliated Hosp 1, Dept Canc Prevent & Control Off, Nanning, Peoples R China; [Fan, Yan-Ping] Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, Canc Ctr, State Key Lab Oncol South China, Guangzhou, Peoples R China; [Feng, Chang-Yan] Chongqing Univ, Canc Hosp, Chongqing Key Lab Translat Res Canc Metastasis &, Chongqing, Peoples R China; [Lian, Xue-Mei] Chongqing Med Univ, Sch Publ Hlth & Management, Chongqing, Peoples R China; [Du, Jing-Chang] Chengdu Med Coll, Sch Publ Hlth, Chengdu, Peoples R China; [Ma, Li] Dalian Med Univ, Publ Hlth Sch, Dalian, Peoples R China; [Qiao, You-Lin] Chinese Acad Med Sci & Peking Union Med Coll, Sch Populat Med & Publ Hlth, Beijing, Peoples R China"

通信作者："Rezhake, R; Qiao, YL (通讯作者)，Xinjiang Med Univ, Affiliated Canc Hosp, Dept Student Affairs, Urumqi, Peoples R China.; Qiao, YL (通讯作者)，Zhengzhou Univ, Affiliated Canc Hosp, Dept Canc Epidemiol, Zhengzhou, Peoples R China.; Qiao, YL (通讯作者)，Henan Canc Hosp, Henan Engn Res Ctr Canc Prevent & Control, Henan Int Joint Lab Canc Prevent, Zhengzhou, Peoples R China.; Ma, L (通讯作者)，Dalian Med Univ, Publ Hlth Sch, Dalian, Peoples R China.; Qiao, YL (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Sch Populat Med & Publ Hlth, Beijing, Peoples R China."

来源：FRONTIERS IN ONCOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001043893200001

JCR分区：Q2

影响因子：3.5

年份：2023

卷号：13

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：colorectal cancer; treatment; decision making; self-reported efficacy; China

摘要："IntroductionThis cross-sectional study evaluated the involvement of patients with advanced colorectal cancer (CRC) in treatment decision-making, assessed the treatment efficacy according to their self-reports, and investigated the influencing factors. MethodsPatients with advanced CRC were recruited from 19 hospitals from March 2020 to March 2021 by a multi-stage multi-level sampling method. A self-designed questionnaire was used to collect demographic and clinical characteristics, involvement of CRC patients in treatment decision-making, treatment methods, and self-reported efficacy. Univariate and unordered multinomial logistic regression analyses were used to evaluate the factors affecting the involvement in treatment decision-making and self-reported efficacy. ResultsWe enrolled 4533 patients with advanced CRC. The average age at diagnosis was 58.7 & PLUSMN; 11.8 years. For the treatment method, 32.4% of patients received surgery combined with chemotherapy, 13.1% of patients underwent surgery combined with chemotherapy and targeted therapy, and 9.7% of patients were treated with surgery alone. For treatment decision-making, 7.0% of patients were solely responsible for decision-making, 47.0% of patients shared treatment decision-making with family members, 19.0% of patients had family members solely responsible for treatment decision-making, and 27.0% of patients had their physicians solely responsible for treatment decision-making. Gender, age, education level, family income, marital status, treatment cost, hospital type, and treatment method were significantly associated with the involvement of patients in treatment decision-making. A total of 3824 patients submitted self-reported efficacy evaluations during treatment. The percentage of patients with good self-reported efficacy was 76.5% (for patients treated for the first time), 61.7% (for patients treated for the second time), and 43.2% (for patients treated after recurrence and metastasis), respectively. Occupation, education level, average annual family income, place of residence, time since cancer diagnosis, hospital type, clinical stage, targeted therapy, and involvement in treatment decision-making were the main influencing factors of self-reported efficacy of treatment. DiscussionConclusively, CRC patients are not highly dominant in treatment decision-making and more likely to make treatment decisions with their family and doctors. Timely and effective communication between doctors and patients can bolster patient involvement in treatment decision-making."

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