Highly sensitive ratiometric fluorescence detection of tetracycline residues in food samples based on Eu/Zr-MOF

作者全名："Zhang, Lei; He, Yuxin; Wu, Yue; Zhang, Jieyuan; Li, Siqiao; Zhang, Zhengwei"

作者地址："[Zhang, Lei; He, Yuxin; Wu, Yue; Zhang, Jieyuan; Zhang, Zhengwei] Chongqing Med Univ, Coll Pharm, Chongqing 400016, Peoples R China; [Li, Siqiao; Zhang, Zhengwei] Chongqing Med Univ, Sch Basic Med Sci, Dept Forens Med, Chongqing 400016, Peoples R China; [Li, Siqiao] Chongqing Key Lab Forens Med, Chongqing 400016, Peoples R China"

通信作者："Li, SQ; Zhang, ZW (通讯作者)，Chongqing Med Univ, Sch Basic Med Sci, Dept Forens Med, Chongqing 400016, Peoples R China."

来源：FOOD CHEMISTRY

ESI学科分类：AGRICULTURAL SCIENCES

WOS号：WOS:001096993600001

JCR分区：Q1

影响因子：8.5

年份：2024

卷号：436

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Eu/Zr-MOF; Ratiometric fluorescence; TC detection; Fluorescence quenching mechanism

摘要："The development of a simple, rapid, and sensitive method for monitoring antibiotic residues is crucial for maintaining food safety. Herein, a ratiometric fluorescence probe based on bimetallic organic framework (Eu/ZrMOF) was developed for the detection of tetracycline (TC). The Eu/Zr-MOF was synthesized by the coordination of Eu3+ and Zr4+ with 2-APDC, which exhibited a grape-like cluster morphology and dual-emitting fluorescence at 430 nm/616 nm. Based on the internal filtering effect (IFE), significant fluorescence quenching was observed at 430 nm, whereas only slight changes occurred at 616 nm. The ratiometric sensing offered two broad linear ranges (0.5-8 mu g/mL; 10-60 mu g/mL) and a low detection limit (26.7 ng/mL). The proposed method was applied to the determination of TC in pork and water samples. Fluorescent sensors have the advantages of simple design, fast response, and high sensitivity, thus providing a promising means for evaluating the safety of food contaminated with TC."

基金机构："National Natural Science Foundation of China [82003713, 82002254]; Natural Science Foundation of Chongqing [cstc2020jcyj-msxmX0158, cstc2021jcyj-msxmX0119]; Science and Technology Research Program of Chongqing Munic-ipal Education Commission [KJQN202200464, KJQN202300457]; CQMU Program for Youth Innovation in Future Medicine [W0095, W0152]"

基金资助正文："This work was funded by the National Natural Science Foundation of China (82003713 and 82002254) , the Natural Science Foundation of Chongqing (cstc2020jcyj-msxmX0158 and cstc2021jcyj-msxmX0119) , the Science and Technology Research Program of Chongqing Munic-ipal Education Commission (KJQN202200464 and KJQN202300457) , and CQMU Program for Youth Innovation in Future Medicine (W0095 and W0152) ."