Application of the 'online assessment plus FOBT at home' to improve participation and the efficacy of opportunistic screening for colorectal cancer: a retrospective cohort study

作者全名："Peng, Xudong; Tang, Gang; Wang, Yonghong; Zeng, Fanling; Chen, Yuedong; Zhang, Weidan; Mo, Chunmei; Yang, Yana; Li, Shuang; Bai, Lian; Xiao, Dachun; Zheng, Guolian; Ran, Wenhua; Chen, Cheng; Yang, Yonghong; Gao, Yuanze; Zhu, Shuangwei; Huang, Zheng; Zhao, Dongqing; Wu, Chaofeng; Xu, Li; Wei, Zhengqiang"

作者地址："[Peng, Xudong; Tang, Gang; Li, Shuang; Huang, Zheng; Zhao, Dongqing; Wu, Chaofeng; Wei, Zhengqiang] hongqing Med Univ, Gastrointestinal Surg Unit, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400000, Peoples R China; [Wang, Yonghong; Zeng, Fanling; Yang, Yana; Xu, Li] Chongqing Med Univ, Hlth Management Ctr, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400000, Peoples R China; [Chen, Yuedong; Zhang, Weidan] Peoples Hosp Tongliang Dist, Dept Gastrointestinal Surg, Chongqing, Peoples R China; [Mo, Chunmei] Peoples Hosp Tongliang Dist, Hlth Management Ctr, Chongqing, Peoples R China; [Bai, Lian; Xiao, Dachun] Chongqing Med Univ, Gastrointestinal Surg Unit, Yongchuan Hosp, Chongqing, Peoples R China; [Zheng, Guolian] Chongqing Med Univ, Yongchuan Hosp, Dept Hlth Management, Chongqing, Peoples R China; [Ran, Wenhua; Chen, Cheng] Qianjiang Cent Hosp, Dept Gen Surg, Chongqing, Peoples R China; [Yang, Yonghong] Qianjiang Cent Hosp, Dept Hlth Management, Chongqing, Peoples R China; [Gao, Yuanze] Ninth Peoples Hosp Chongqing, Anorectal Dept, Chongqing, Peoples R China; [Zhu, Shuangwei] Fuling Peoples Hosp Chongqing, Gastroenteroanal Surg, Chongqing, Peoples R China"

通信作者："Wei, ZQ (通讯作者)，hongqing Med Univ, Gastrointestinal Surg Unit, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400000, Peoples R China.; Xu, L (通讯作者)，Chongqing Med Univ, Hlth Management Ctr, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400000, Peoples R China."

来源：BMC PUBLIC HEALTH

ESI学科分类：SOCIAL SCIENCES, GENERAL

WOS号：WOS:001127382900007

JCR分区：Q1

影响因子：3.5

年份：2023

卷号：23

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Colorectal cancer (CRC); Opportunistic screening; Social; Media; Fecal occult blood test (FOBT); Colonoscopy

摘要："Background Colorectal cancer (CRC) screening faces two major challenges: insufficient screening coverage and poor adherence. A smartphone applet named ""Early Screening Assistant (ESA)"" was developed to create an online risk-assessment and fecal occult blood test (FOBT) at home. This retrospective study was designed to evaluate whether the new CRC screening strategy can improve the colonoscopy participation rate (PR) and lesion detection rate (DR).Methods In total, 6194 individuals who accepted normal health examinations and CRC screening based on the ESA from June 2020 to May 2022 were assigned to the ESA group. Accordingly, 7923 inhabitants who only accepted normal health examinations were assigned to the control group. The colonoscopy PR and neoplastic lesion DR were then compared between the two groups.Results Overall, a higher proportion of subjects in the ESA group (285 of 6194 [4.6%]) completed colonoscopy than in the control group (126 of 7923, [1.6%]), p < 0.01). The neoplastic lesion DR also significantly increased in the ESA group (76 of 6194 [1.22%]) compared with the control group (15 of 7923 [0.19%]) (p < 0.01). The adjusted diagnostic sensitivity and specificity of the ""Online assessment + FOBT at home"" were 41.5% and 62.6% for neoplastic lesions, respectively.Conclusions This retrospective cohort study confirmed that the new CRC screening strategy based on the ""Online assessment + FOBT at home"" can improve colonoscopy participation and the neoplastic lesion detection rate and may represent a promising screening strategy for CRC."

基金机构：Chongqing key diseases Research and Application Demonstration Program from Chongqing Municipal Health Commission (Colorectal Cancer prevention and Treatment Technology Research and Application Demonstration [No. 2019ZX003])

基金资助正文：We thank International Science Editing (http://www.internationalscienceediting.com) for editing this manuscript.