Individual resting-state network functional connectivity predicts treatment improvement of repetitive transcranial magnetic stimulation in major depressive disorder: A pilot study

作者全名："Long, Zhiliang; Du, Lian; Marino, Marco"

作者地址："[Long, Zhiliang] Southwest Univ, Fac Psychol, Sleep & NeuroImaging Ctr, Chongqing, Peoples R China; [Du, Lian] Chongqing Med Univ, Affiliated Hosp 1, Dept Psychiat, Chongqing, Peoples R China; [Marino, Marco] Katholieke Univ Leuven, Movement Control & Neuroplast Res Grp, Leuven, Belgium; [Marino, Marco] Univ Padua, Dept Gen Psychol, Padua, Italy"

通信作者："Long, ZL (通讯作者)，Southwest Univ, Fac Psychol, Sleep & NeuroImaging Ctr, Chongqing, Peoples R China."

来源：PSYCHIATRY RESEARCH

ESI学科分类：PSYCHIATRY/PSYCHOLOGY

WOS号：WOS:001133671300001

JCR分区：Q1

影响因子：11.3

年份：2024

卷号：331

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Repetitive transcranial magnetic stimulation; Major depressive disorder; Resting-state network

摘要："The current pilot study aimed to exploratively investigate whether individual functional connectivity (FC) of the rTMS stimulation site with resting-state networks could predict the individual efficacy of rTMS treatment. We found that rTMS induced an increase of the FC between the stimulation site and the limbic network (LN) in healthy participants, and that this individualized FC was negatively correlated with the rTMS treatment improvement in MDD patients. Moreover, the LN successfully guided the personalized rTMS therapy. These findings highlighted the crucial role of the LN in understanding the mechanisms underlying rTMS treatment improvement, and the personalized therapy in MDD patients."

基金机构：National Natural Science Foundation of China [81901725]

基金资助正文：We thank Gabriel Castrillon and the colleagues for providing the online datasets (https://openneuro.org/datasets/ds001927/versions/2.0.2) . This work was supported by the National Natural Science Foundation of China (81901725) .