Extended lymphadenectomy based on the TRIANGLE for pancreatic head cancer: a single-center experience

作者全名："Lei, Kai; Wang, Jiaguo; Wang, Xingxing; Wang, Hongxiang; Hu, Run; Zhang, Huizhi; Xu, Wei; Xu, Jie; You, Ke; Liu, Zuojin"

作者地址："[Lei, Kai; Wang, Jiaguo; Wang, Xingxing; Wang, Hongxiang; Hu, Run; Zhang, Huizhi; Xu, Jie; You, Ke; Liu, Zuojin] Chongqing Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 2, Chongqing 400000, Peoples R China; [Xu, Wei] Peoples Hosp Liangping Dist, Dept Hepatobiliary Breast & Thyroid Surg, Chongqing 405200, Peoples R China"

通信作者："Liu, ZJ (通讯作者)，Chongqing Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 2, Chongqing 400000, Peoples R China."

来源：LANGENBECKS ARCHIVES OF SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001156245000001

JCR分区：Q2

影响因子：2.1

年份：2024

卷号：409

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Lymphadenectomy; Pancreaticoduodenectomy; Pancreatic head cancer; Progression; TRIANGLE

摘要："BackgroundThis study was to compare the safety and efficacy of different lymphadenectomy methods in patients with pancreatic head cancer undergoing pancreaticoduodenectomy (PD).Material and methodsA total of 150 patients were included in this study. Patients were divided into Group A (n = 79), Group B (n = 44), and Group C (n = 27) according to the different lymphadenectomy methods. The clinical endpoint was time to progression (TTP) and overall survival (OS). Postoperative complications of different lymphadenectomy methods were compared respectively. TTP and OS of the three groups were compared by Kaplan-Meier curves.ResultsThere were no significant differences between the three groups in operative time (P = 0.300), death in the hospital (P = 0.253), postoperative hemorrhage (P = 0.863), postoperative pancreatic fistula (POPF) B/C (P = 0.306), bile leakage (P = 0.215), intestinal fistula (P = 0.177), lymphatic leakage (P = 0.267), delayed gastric emptying [(DGE) (P = 0.283)], ICU stay (P = 0.506), and postoperative hospital stay [(PHS) (P = 0.810)]. Median TTP in Groups B and C was significantly longer than in Group A (log-rank test, A vs B: P = 0.0005, A vs C: P = 0.0001). Median OS between the three groups has no statistical difference (P = 0.1546).ConclusionsExtended lymphadenectomy methods based on the TRIANGLE do not increase perioperative complications significantly and can effectively delay tumor progression in patients with pancreatic head cancer."

基金机构：National Natural Science Foundation of China

基金资助正文：No Statement Available