Evaluation of endometrial receptivity in women with unexplained infertility by shear wave elastography

作者全名："Li, Zheng-ying; Cai, Lu; Zhang, Zhi-jun; Zou, Hai-rong; He, Mei; Qin, Mei-lin; Wang, Hui"

作者地址："[Li, Zheng-ying; Cai, Lu; Zhang, Zhi-jun; Zou, Hai-rong; He, Mei; Qin, Mei-lin; Wang, Hui] Chongqing Med Univ, Univ Town Hosp, Dept Ultrasound, 55 Univ Middle Rd, Chongqing 401331, Peoples R China"

通信作者："Wang, H (通讯作者)，Chongqing Med Univ, Univ Town Hosp, Dept Ultrasound, 55 Univ Middle Rd, Chongqing 401331, Peoples R China."

来源：INSIGHTS INTO IMAGING

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001189383600002

JCR分区：Q1

影响因子：4.1

年份：2024

卷号：15

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Endometrial receptivity; Endometrium; Elasticity; Shear wave elastography; Unexplained infertility

摘要："Objectives The endometrium of most unexplained infertility (UI) patients has been altered histologically. Shear wave elastography (SWE) is utilized to assess the signature of living tissue. This study aimed to explore the value of SWE in evaluating endometrial receptivity (ER) in UI patients. Methods In total, 59 UI patients (UI group) and 52 normal control women (NC group) who received fertility consultation in our hospital were included between January 2022 and June 2023. We divided them into the late-proliferative phase of UI group (LPUI; n = 59), mid-secretory phase of UI group (MPUI; n = 41), late-proliferative phase of NC group (LPNC; n = 52), and mid-secretory phase of NC group (MPNC; n = 45). Transvaginal ultrasonography and SWE were performed during the LP and MP. Endometrial thickness (EMT), uterine artery pulsatility index (UA-PI), endometrial mean elasticity (E-mean), and mean shear wave velocities (SWV-mean) were measured. Results There were significant differences in E-mean, SWV-mean, EMT, and UA-PI between the UI group and the NC group during both the LP and MP (p (MPNC vs MPUI) < 0.05, p (LPNC vs LPUI) < 0.05). E-mean and SWV-mean decreased with increasing EMT but increased with increasing UA-PI (p < 0.05). The most effective parameter for evaluating ER in UI patients is the E-mean (AUC = 0.89). Conclusions UI patients exhibited thinner endometrium, increased endometrial stiffness, and poor endometrial blood perfusion. E-mean was the most effective parameter to evaluate ER in UI patients. The study preliminarily proved that SWE is a promising non-invasive tool for evaluating the condition of endometrium."

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