Simplified Chinese version of the PROMIS Pediatric-25 profile: A validation study among cancer children
作者全名：Li, Danyu; Huang, Yueshi; Wu, Fulei; Huang, Qingmei; Liu, Yang; Yao, Juan; Shen, Nanping; Wang, Yingwen; Yu, Ling; Yuan, Changrong; Zhang, Wen
作者地址：[Li, Danyu; Wu, Fulei; Huang, Qingmei; Yuan, Changrong; Zhang, Wen] Fudan Univ, Sch Nursing, Shanghai, Peoples R China; [Huang, Yueshi] Fudan Univ, Shanghai Canc Ctr, Dept Nursing, Shanghai, Peoples R China; [Huang, Yueshi] Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai, Peoples R China; [Liu, Yang; Yao, Juan] Chongqing Med Univ, Childrens Hosp, Chongqing, Peoples R China; [Shen, Nanping] Shanghai Jiao Tong Univ, Shanghai Childrens Med Ctr, Sch Med, Shanghai, Peoples R China; [Wang, Yingwen; Yu, Ling] Fudan Univ, Childrens Hosp, Shanghai, Peoples R China
通信作者：Yuan, CR; Zhang, W (通讯作者)，Fudan Univ, Sch Nursing, Shanghai, Peoples R China.
来源：JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES
ESI学科分类：SOCIAL SCIENCES, GENERAL
WOS号：WOS:001207587900001
JCR分区：Q2
影响因子：2.1
年份：2024
卷号：75
期号：
开始页：e1
结束页：e9
文献类型：Article
关键词：Patient -reported outcomes; Pediatric cancer; Psychometric validation
摘要：Purpose: Pediatric cancer is a significant health concern in China, and evaluating the impact of cancer and its treatment on the well-being of young patients is essential for both clinical care and research purposes. This study aimed to psychometrically validate the Patient -reported Outcomes Measurement Information System Pediatric -25 Profile (PROMIS-Pediatric-25) among Chinese children with cancer. Design and methods: We enrolled a group of 114 children living with cancer between the ages of 8 and 17. Each participant completed questionnaires that covered sociodemographic and clinical information and the PROMISPediatric-25. The floor and ceiling effect was examined. Cronbach's alpha and split -half coefficient were examined to determine the reliability. Factor structure was explored by factor analysis. Three assumptions of Rasch model -based item response theory (IRT) were assessed. Differential item functioning (DIF) was investigated concerning factors of gender, diagnosis, and treatment stage. Results: The floor or ceiling effects were detected for six domains. The reliability was found to be excellent. Furthermore, the factor structure of these six domains was validated. Our analysis confirmed that the assumptions required for IRT were met with acceptable unidimensionality, local independence, and good monotonicity. Additionally, we observed measurement equivalence, with outstanding levels of DIF across factors such as gender, diagnosis, and treatment stage. Conclusion: PROMIS-Pediatric 25 is a highly reliable and valid instrument for evaluating key domains of healthrelated quality of life in Chinese pediatric cancer patients. Practice implication: Nursing practice could engage the PROMIS-Pediatric 25 for accurate and quick children symptom and function assessment. (c) 2023 Elsevier Inc. All rights reserved.
基金机构：Clinical Research in Health Industry of Shanghai Municipal Health Commission -Youth Program [20224Y0123]; Fuxing Nursing Research Fund of Fudan University [FNF202205]
基金资助正文：We acknowledge the funding from the Clinical Research in Health Industry of Shanghai Municipal Health Commission -Youth Program (20224Y0123) and the Fuxing Nursing Research Fund of Fudan University (FNF202205) .
