Risk factors for malnutrition in patients with diabetic foot ulcer and its association with prolonged length of hospitalization

作者全名：Ran, Qian; Xu, Weiwei; Zhao, Xili; Sun, Hang; Liu, Li; Luo, Yunqiu

作者地址：[Ran, Qian; Xu, Weiwei; Zhao, Xili; Sun, Hang; Liu, Li; Luo, Yunqiu] Chongqing Med Univ, Affiliated Hosp 2, Dept Endocrinol, Chongqing, Peoples R China; [Zhao, Xili] Chongqing Med Univ, Clin Coll 2, Chongqing, Peoples R China

通信作者：Xu, WW (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Endocrinol, Chongqing, Peoples R China.

来源：NUTRITION & DIABETES

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001227185700002

JCR分区：Q1

影响因子：4.6

年份：2024

卷号：14

期号：1

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结束页：　

文献类型：Article

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摘要：Purpose: The study was designed to investigate the occurrence and risk factors of malnutrition in diabetic foot ulcers (DFU) patients and examine the association between malnutrition and length of stay (LOS). Methods: This observational study included DFU hospitalized patients in two campuses of a hospital from January 2021 to June 2023. The diagnosis standard of malnutrition was established by using the Global Leadership Initiative on Malnutrition (GLIM) criteria. Patients were followed up to ascertain the length of hospitalization, and hospital stays longer than 17 days were considered as prolonged LOS. To explore the risk factors of malnutrition and the association between malnutrition and LOS, univariate and multivariate logistic regression analyses were performed. Results: Overall 219 DFU patients were enrolled, malnutrition was identified in 38.36% of patients according to GLIM criteria, and 92 patients (42%) were recognized as prolonged LOS. Logistic regression analyses showed that BMI (P <0.001), Alb (P = 0.002), HbA1c (P <0.001), ulcer infection (P <0.001), LOS (P = 0.010), and ABI (P = 0.024) were independent risk factors for malnutrition. Besides, malnutrition by GLIM criteria was closely related to prolonged LOS and malnourished DFU patients were 2.857 times (95% CI, 1.497-5.450; P = 0.001) likely to present prolonged LOS than that of normal nutrition. Conclusion: Malnutrition was considered to be extremely prevalent in DFU patients and was associated with approximately three times higher likelihood of prolonged LOS. Implementing and disseminating the diagnostic criteria during routine practice is crucial, given the predictive efficacy of GLIM criteria.

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