Clinical characteristics of heavy alcohol consumption in young and middle-aged acute cerebral infarction: A 12-month follow-up study

作者全名：Liao, Jia; Li, Xin; Wang, Ling; Chen, Mingfen; Quan, Fengying; Xi, Zhiqin

作者地址：[Liao, Jia; Li, Xin; Wang, Ling; Chen, Mingfen; Quan, Fengying; Xi, Zhiqin] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing, Peoples R China; [Liao, Jia; Li, Xin; Wang, Ling; Chen, Mingfen] Chongqing Med Univ, Coll Nursing, Chongqing, Peoples R China; [Liao, Jia; Quan, Fengying] Chongqing Med Univ, Affiliated Hosp 1, Dept Nursing, Chongqing, Peoples R China

通信作者：Quan, FY; Xi, ZQ (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing, Peoples R China.

来源：HELIYON

ESI学科分类：　

WOS号：WOS:001239032600001

JCR分区：Q1

影响因子：3.4

年份：2024

卷号：10

期号：9

开始页：　

结束页：　

文献类型：Article

关键词：Acute cerebral infarction; Heavy alcohol consumption; Young and middle-aged patients

摘要：Objective: To investigate the clinical characteristics and prognosis of heavy alcohol consumption among young and middle-aged patients with acute cerebral infarction (ACI). Methods: A total of 263 young and middle-aged ACI patients were included in the study from June 2018 to December 2020 and classified into heavy drinkers and non-heavy drinkers. Multivariate logistic regression analysis was conducted to assess the association between ACI and heavy alcohol consumption, considering clinical characteristics and one-year post-discharge prognosis. Results: Among the patients, 78 were heavy drinkers. Heavy drinkers were more likely to consume alcohol 24 h before ACI onset (OR 4.03, 95 % CI 2.26 -7.20), especially in the form of liquor (OR 3.83, 95 % CI 1.59 -9.20), and had a higher risk of diastolic blood pressure >= 90 mmHg upon admission (OR 2.02, 95 % CI 1.12 -3.64). In the one-year post-discharge prognosis, heavy drinkers had a greater likelihood of poor prognosis at 3 months (OR 2.31, 95 % CI 1.01 -5.25), were less likely to quit drinking after discharge (OR 0.36, 95 % CI 0.19 -0.66), and had a higher risk of recurrent cerebral infarction (OR 2.79, 95 % CI 1.14 -6.84). Conclusions: Over the 12-month follow-up, young and middle-aged ACI patients with heavy alcohol consumption exhibited worse short-term prognosis. Controlling alcohol consumption levels may improve the prognosis of these patients.

基金机构：Chongqing Key Specialty Construction Project: Fine Course Construction Project for Clinical Nursing grant [0203 2023 47-202336]

基金资助正文：The authors disclosed receipt of the following financial support for the research: this work was supported by Chongqing Key Specialty Construction Project: Fine Course Construction Project for Clinical Nursing grant (grant number 0203 2023 47-202336) .