Heart/breathing rate ratio (HBR) as a predictor of mortality in critically ill patients

作者全名：Zhang, Tong Yan; Hou, Ya Zhu; Du, Ya Jun; Du, Qian; Dou, Hai Rong; Gao, Xiu Mei

作者地址：[Zhang, Tong Yan; Dou, Hai Rong] Tianjin Univ Tradit Chinese Med, Affiliated Hosp 2, Infect Dis Dept, Tianjin, Peoples R China; [Hou, Ya Zhu] Teda Int Cardiovasc Hosp, Tianjin, Peoples R China; [Hou, Ya Zhu] Tianjin Univ Tradit Chinese Med, Teaching Hosp 1, Natl Clin Res Ctr Chinese Med Acupuncture & Moxibu, Dept Cardiol, Tianjin, Peoples R China; [Du, Qian] Chongqing Med Univ, Affiliated Hosp 3, Dept Pharm, Chongqing, Peoples R China; [Gao, Xiu Mei] Tianjin Univ Tradit Chinese Med, Tianjin State Key Lab Modern Chinese Med, Poyang Lake Rd, Tianjin 301617, Peoples R China

通信作者：Gao, XM (通讯作者)，Tianjin Univ Tradit Chinese Med, Tianjin State Key Lab Modern Chinese Med, Poyang Lake Rd, Tianjin 301617, Peoples R China.

来源：HELIYON

ESI学科分类：　

WOS号：WOS:001243896300001

JCR分区：Q1

影响因子：3.4

年份：2024

卷号：10

期号：10

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结束页：　

文献类型：Article

关键词：Heart/breathing rate ratio; Mortality; Risk stratification; Critically ill patients

摘要：Objectives: The early prediction of death is a challenge for medical staff. We evaluated the ability of the heart/breathing rate ratio (HBR) to predict mortality. Methods: This was a single-center retrospective observational study of adult patients who had fever with or without respiratory symptoms, who survived at least 2 h after visiting the hospital, and whose lactate levels and vital signs were tested. We evaluated the distribution of mortality at different HBR levels and compared HBR with lactate. Results: A total of 18,872 fever clinic visits were screened, and 183 patients whose lactate levels were tested were recruited. Patients who had HBR values lower than 4.5 or higher than 5.5 had greater mortality than patients who had HBR values between 4.5 and 5.5 (21.3 % vs. 3.4 %, p = 0.003; 28.9 % vs. 3.4 %, p < 0.001, respectively). In patients whose HBR was <5, the AUROC for HBR for mortality was 0.762 (95 % CI: 0.643-0.880), and that for lactate was 0.701 (95 % CI: 0.564-0.837). In patients whose HBR was >= 5, the AUROC for HBR for mortality was 0.721 (95 % CI: 0.584-0.857), and that for lactate was 0.742 (95 % CI: 0.607-0.848). Conclusions: HBR is helpful for stratifying mortality risk among critically ill patients in acute care clinics for infectious diseases.

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