Effect of 52 % low-sodium salt applied to CM-DASH diet on atherosclerotic cardiovascular disease risks in patients with hypertension and type-2 diabetes

作者全名："Tang, Jie; Chen, Dan; Mu, Lisha; Yu, Pingping; Gong, Tao; Xu, Huini; Zhang, Ziyan; Cai, Shuwen; Mu, Lihong; Mei, Ying"

作者地址："[Tang, Jie; Chen, Dan; Mu, Lisha; Gong, Tao; Zhang, Ziyan; Cai, Shuwen; Mu, Lihong] Chongqing Med Univ, Innovat Ctr Social Risk Governance Hlth, Dept Epidemiol, Sch Publ Hlth & Management,Res Ctr Med & Social, Chongqing, Peoples R China; [Yu, Pingping; Mei, Ying] Chongqing Med Univ, Affiliated Hosp 2, Hlth Management Ctr, Chongqing, Peoples R China; Chongqing Nanan Dist Peoples Hosp, Chongqing, Peoples R China"

通信作者："Mu, LH (通讯作者)，Chongqing Med Univ, Dept Epidemiol, Sch Publ Hlth & Management, 1 Yixueyuan Road, Chongqing 400016, Peoples R China."

来源：NUTRICION HOSPITALARIA

ESI学科分类：AGRICULTURAL SCIENCES

WOS号：WOS:000886613000010

JCR分区：Q4

影响因子：1.2

年份：2022

卷号：39

期号：4

开始页：778

结束页：785

文献类型：Article

关键词：Hypertension; Type-2 diabetes; DASH diet; Low-sodium salt; Risk of cardiovascular disease; Diet compliance

摘要："Introduction: hypertension and diabetes are chronic disorders associated with an increased risk of cardiovascular disease. Objectives: to evaluate the effect of 52 % low-sodium salt applied to the Chinese-modified DASH (CM-DASH) diet on risk of atherosclerotic scalar disease (ASCVD) in patients with hypertension and type-2 diabetes. Methods: the low-sodium salt group (LSSG) took 5 g/day of 52 % low-sodium salt plus CM-DASH diet for 8 weeks, while the normal-sodium salt group (NSSG) took the same dose of normal-sodium salt plus CM-DASH diet for 8 weeks. Blood tests, 24-hour urine tests, anthropometric measurements, and 10-year risk of ASCVD prediction were assessed. Results: compared with baseline, both LSSG and NSSG showed a significant reduction in 10-year risk of ASCVD, but we did not find any statistically significant differences in 10-year risk of ASCVD between LSSG and NSSG. Conclusions: our study shows that salt limits and DASH diets reduce the risk of cardiovascular disease whereas low-sodium salt containing 52 % sodium chloride did not significantly lower the risk of cardiovascular disease when compared to regular salt. Due to the limitations of the research, additional studies will be necessary to confirm our findings."

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