关键词： 血液学   基础医学   急性造血功能停滞  

摘要： 急性造血功能停滞国外1937年首次报告,国内为1964年。本文是我院1979年1月—1982年2月确诊的5例,现报道如下。临床及血液学资料分别见表1、2。

关键词： 急性病   血液病/诊断   造血系统  

关键词： Flow   Medical   Cytochemistry   Hematology  

关键词： 细胞分离/仪器和设备  

摘要： The hematological changes, temperature. pulse, respiration, body weight and clinical manifestations were observed one hour before and after blood-element-pheresis in 100 random--selected donors. On the basis of different blood elements taken, number of cycles performed, and types of solution (ACD or HES) used , variations in the different groups were studied. The study aimed at the evaluation of the effect on the donors from whom large amouut of luecocytes and platelets were collected with HM 30 processor. The operation of pheresis was done by puncturing two veins and infusing ACD-A or HES (MW 45 × 10 4) solution for 2-8 hours. Among the parameters recorded most of them showed a tendency to decrease, the mean of the general reduction being 9-20.1% and that of platelet count, 15, 8-53.3%. These changes might be due to the collection of large amount of blood elements within a short period of time the infusion of large quantity of ACD and normal saline cau-sing dilution of the blood and the expansion of plasma following injection of HES. During the course of the procedure, transient numbness of the upper extremities occurred ih 6 donors, chills, palpitaiion, shortness of breath, sweating and pallor in 4, perioral tingling sensation in 7 and urinary incontinence in 1. No serious reactions occurred. Thus the application of H-M 30 for leucapheresis and plateletpheresis was satisfactory and acceptably safe. The donors tolerate fairly well 4-8 cycles for 2-8hours

摘要： Reticulocytes in fixed human blood samples were stained for RNA with the fluorescent dye pyronin Y and measured by flow cytometry. The resulting relative frequency distributions of the RNA fluorescence intensities concurred with the different stages in maturation from early reticulocytes to mature red cells. A computer program was written to calculate from these frequency distributions the relative number of reticulocytes, their relative RNA content, and the median of the reticulocyte population (RNA index). This method was applied to 30 healthy blood bank donors (control group), as well as to patients with various hematologic disorders showing abnormal erythropoietic activity. The measured percentage of reticulocytes, RNA content, and RNA index were found to correlate well with the various hematologic disorders. Changes in erythropoiesis could be clearly followed, as was demonstrated by analyzing blood samples from children with aplastic anemia or acute myeloid leukemia, who were treated with allogeneic bone marrow transplantation. Measurements on blood samples from healthy blood bank donors showed that with this method, small changes in the reticulocyte population, such as the appearance of polychromatic erythrocytes in the peripheral blood 5-8 hr after donation, can be detected. The statistical reliability and the information provided on the maturation stage of the entire reticulocyte population make flow cytometry of peripheral blood reticulocytes a more informative method for the study of hematologic abnormalities than conventional methods for reticulocyte counting and classification.

关键词： 生化   大鼠   免疫学测定  

摘要： 本文抽取封闭群大鼠,进行了40余项指标的测定,所得结果如下,供实验动物工作者参考。材料与方法 1.动物来源应用封闭群Wistar大鼠,全部喂固形饲料和水,鼠龄为4个月左右,体重在300克左右,经解剖选择巨观无病变者。

关键词： 重点科室   医疗工作   医疗质量   医技科室   检验科   中心工作   住院医师   科室建设   住院总医师   临床血液学  

摘要： 医院的中心工作是医疗,为了提高医疗质量必须开展临床科研。医疗工作是临床科研的基础和前提,而临床科研又能促进医疗工作的进展和提高,医疗工作与临床科研相辅相成,互相促进。因此,凡是有条件的医疗单位均应积极开展临床科研工作,这是完全必要的又是完全可能的。现将我们组织医院临床科研中积累的初步体会简述如下:一、发挥优势。

关键词： Animals   Antibodies, Antinuclear   Bone Marrow Transplantation   Chronic Disease   Esophagus/pathology   Female   Graft vs Host Reaction*   Hematocrit   Hematocrit   Immunoglobulin M   Intestines/pathology   Leukocyte Count   Leukocyte Count   Liver/immunology   Liver/pathology   Lymph Nodes/pathology   Radiation Chimera*   Rats   Rats, Inbred ACI   Rats, Inbred Lew   Salivary Glands/pathology   Skin/immunology   Skin/pathology   Spleen/pathology   Thymus Gland/pathology   Time Factors   Tongue/immunology   Tongue/pathology  

摘要： The clinical features, pathology, and immunopathology of chronic graft-versus-host disease (GVHD) developing in the long-term rat radiation chimera are described. At 6 to 12 months post-transplant, the previously stable ACI/LEW chimeras developed patchy to diffuse severe hair loss and thickened skin folds, and had microscopic features resembling scleroderma, Sjogren's syndrome, and chronic hepatitis. Skin histology showed dermal inflammation and acanthosis with atrophy of the appendages, with progression to dermal sclerosis. The liver revealed chronic hepatitis with bile duct injury and proliferation and periportal piecemeal necrosis. The tongue had considerable submucosal inflammation, muscular necrosis, and atrophy and arteritis. The serous salivary glands, lacrimal glands, and bronchi had lymphocytic inflammation and injury to duct, acinar, and mucosal columnar epithelium. The thymus had lymphocyte depletion of the medulla with prominent epithelium. The spleen and lymph nodes had poorly developed germinal centers but increased numbers of plasma cells. IgM was observed along the basement membrane and around the basal cells of the skin and tongue and along the basement membrane of the bile ducts. IgM was present also in the arteries of the tongue. Immunoglobulins eluted from the skin cross-reacted with the bile duct epithelium and usually with both ACI and Lewis skin. Increased titers of speckled antinuclear antibodies were present in the serum of rats with chronic GVHD. Chronic GVHD in the long-term rat radiation chimera is very similar to human chronic GVHD and is a potentially excellent model for autoimmune disorders including scleroderma, Sjogren's syndrome, and chronic hepatitis.(C) Williams & Wilkins 1982. All Rights Reserved.

关键词： 创伤性心包炎   网胃   心包   外物   沉降率   前胃   红细胞   红血球   乳牛   拍水音   白细胞   白血球   基础医学   血液学  

摘要： 创伤性心包炎是由外物刺破网胃进入心包的结果。这样,导致了渗出、化脓或纤维素性心包炎,由于粘连或心包内压增加而妨碍了正常心肺机能。本文叙述被送至Hissar兽医研究学院临床课部的十例Haryana杂交乳牛创伤性心包炎的临床观察和血液