关键词:
抗氧化剂/治疗应用
自主神经系统疾病/病因学
自主神经系统疾病/病理生理学
自主神经系统疾病/预防和控制
自主神经系统疾病/心理学
复方合剂
精神障碍/病因学
精神障碍/病理生理学
精神障碍/预防和控制
精神障碍/心理学
心理生理学
应激
心理学/并发症
应激
心理学/病理生理学
应激
心理学/心理学
维生素A/治疗应用
维生素E/治疗应用
维生素K/治疗应用
成年人
女(雌)性
人类
男(雄)性
摘要:
Autonomic dysfunction in chronic emotional stress is well documented. The aim of this study was to analyze the effects of natural antioxidant vitamin E (aekol). Twenty persons (16 women and 4 men, mean age 38 +/- 4 years) who reported recent occurrence of emotional stress were examined before and after a 4-week treatment with aekol (5 ml twice a day). Heart rate variability (taking into account very low-frequency (VLF, 0.003-0.04 Hz), low-frequency (LF, 0.04-0.15 Hz), and high-frequency (HF, 0.15-0.40 Hz) components) was computed from the power spectra (5-min epochs) of the EKG recorded in the patients in supine position. After the treatment, the HF power of the heart rate variability (an index of cardiac parasympathetic activity) increased (p < 0.05), whereas the VLF power (an index of the cerebral sympathetic activity) decreased (p < 0.01). The decrease in the VLF was accompanied by a reduction of anxiety level (p < 0.01). According to our hypothesis, the absolute and relative power of the VLF can be used as an index of anxiety or cerebral sympathetic activity, which significantly decreases after the aekol treatment.