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Silver nitrate mimicking a foreign body in the pharyngeal mucosal space

World Journal of Radiology 2015年第5期7卷 100-103页

作者： Devon Livingstone Yazeed Alghonaim Nathan Jowett Eyal Sela Alex Mlynarek Reza Forghani Department of Otolaryngology–Head and Neck Surgery University of Calgary Department of Otolaryngology–Head and Neck Surgery Mc Gill University Department of Radiology Sir Mortimer B. Davis Jewish General Hospital and Mc Gill University

Silver nitrate is sometimes used as a means of chemicalcauterization for control of minor bleeding and management of hypergranulation tissue following bedside head and neck procedures. There are only few reports available on the imaging appearance of silver nitrate and its potential to mimic a foreign body. We report a case of a patient presenting with dysphagia, odynophagia, and fever following dental work who had a peritonsillar incision and drainage for treatment of a deep neck space infection. During the procedure, silver nitrate was applied to halt the bleeding. Patient was subsequently transferred to another institution. Since the patient was not showing significant clinical improvement on antibiotic therapy, a computed tomography(CT) scan was performed demonstrating a hyperdense structure lodged in the pharyngeal mucosal space in the oropharynx and soft palate that was mistaken for a foreign body such as bone. Silver nitrate can have density similar to bone but does not have the normal architecture of bone with cortex and marrow on CT. Familiarity with the appearance of silver nitrate on CT, lack of bone architecture, and proper documentation and communication of the use of silver nitrate to the consultant radiologist and medical personnel could help avoid misdiagnosis and potentially unnecessary surgical exploration.

关键词： Silver nitrate Computed tomography Bony foreign body Soft tissues neck Deep neck infections pharyngeal mucosal space

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Exposure to cadmium and head and neck cancers: a meta-analysis of observational studies

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REVIEWS ON ENVIRONMENTAL HEALTH 2021年第4期36卷 577-584页

作者： Rezapour, Maysam Rezapour, Habib Allah Chegeni, Maryam Khanjani, Narges Kerman Univ Med Sci Sch Publ Hlth Environm Hlth Engn Res Ctr Kerman *** Iran Kerman Univ Med Sci Sch Publ Hlth Dept Biostat & Epidemiol Kerman *** Iran Mazandaran Univ Med Sci Amol Fac Paramed Sci Sari Iran Mazandaran Univ Med Sci Mahmood Abad Hlth & Care Network Sari Iran

Cadmium (Cd) is a widespread environmental pollutant. A number of observational studies have reported that Cd might be a cause of nasopharyngeal (NPC), pharyngeal (PC), or laryngeal cancers (LC). In this study evidence about the relation of Cd and NPC, PC, and LC has been summarized. A literature review was conducted until 20 June 2020 in PubMed, Ovid, Scopus, Web of Science and Google scholar databases to investigate the epidemiologic evidence for the relation between cadmium exposure and cancers of the nasopharynx, pharynx, and larynx. Ten articles were selected after careful screening of retrieved studies. All of these studies obtained a Newcastle-Ottawa Scale (NOS) quality score from 6 to 8. Due to high hetero-geneity, in all analyses, random effect was used. The pooled results showed that cadmium levels in NPC (standard mean difference (SMD=0.55;95% CI=0.20, 0.89;p=0.002) and PC (SMD=9.79;95% CI=0.62, 18.96;p=0.036) patients/tissues were significantly higher than their controls. But cadmium levels were not significantly different between LC cases/ tissues and their controls. (SMD=-0.05;95% CI=-0.99, 0.89;p=0.921). Exposure to cadmium is likely to cause nasopharyngeal and pharyngeal cancer.

关键词： cadmium cancer laryngeal nasopharyngeal pharyngeal

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Long-Term Outcomes of End-Flexible-Rigidscopic Transoral Surgery for Pharyngolaryngeal Cancer

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LARYNGOSCOPE 2023年第6期133卷 1415-1424页

作者： Watanabe, Yoshiki Tanaka, Shinzo Hasebe, Koki Hiratsuka, Yasuyuki Yoshida, Takao Kusano, Junko Hori, Shusei Okamura, Kana Tanaka, Chisato Fujikawa, Shiori Osada, Yuka Minoyama, Manabu Japanese Red Cross Osaka Hosp Dept Otolaryngol Head & Neck Surg 5 30 Fudegasaki Tennoji Osaka 5438555 Japan Kyoto Univ Grad Sch Med Dept Otolaryngol Head & Neck Surg Kyoto Japan Uji Tokushukai Med Ctr Dept Otolaryngol Head & Neck Surg Kyoto Japan Natl Hosp Org Kyoto Med Ctr Dept Otolaryngol Head & Neck Surg Kyoto Japan Japanese Red Cross Wakayama Med Ctr Dept Otolaryngol Wakayama Japan Minoyama Otolaryngol Med Corp Osaka Japan

Objective End-flexible-rigidscopic transoral surgery (E-TOS) is a new and minimally invasive transoral surgery for resection of Tis-selected T3 pharyngolaryngeal cancers. We evaluated long-term oncological outcomes and whether postoperative voice and swallowing function were preserved following E-TOS. Methods In this retrospective single-center study, 154 patients treated with E-TOS using a curved retractor, flexible-tip rigid endoscope, and thin curved instruments were included. Their survival rate, larynx preservation rate, and disease control rate were estimated using the Kaplan-Meier method. Postoperative voice function was evaluated using both objective and subjective tests. Postoperative swallowing function was assessed using the Hyodo score and the functional outcome swallowing scale. Results The 3-year and 5-year overall survival, disease-specific survival, disease-free survival, laryngectomy-free survival, local control, and loco-regional control rates post E-TOS were 89.8% and 82.2%, 95.6% and 92.3%, 78.5% and 70.3%, 87.2% and 80.9%, 93.9% and 92.5%, and 87.2% and 85.7%, respectively. Both objective and subjective postoperative voice and swallowing function tests were within normal limits in more than 90% of the patients. Conclusion E-TOS is an effective, safe, low-cost, and minimally invasive transoral surgery for Tis-selected T3 pharyngolaryngeal cancer;it also preserves postoperative voice, larynx, and swallowing function. Level of Evidence 4 Laryngoscope, 2022

关键词： endoscopic pharyngeal laryngeal transoral minimally invasive

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Haemophilus influenzae type b reemergence after combination immunization

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EMERGING INFECTIOUS DISEASES 2006年第6期12卷 937-941页

作者： Johnson, Nik G. Ruggeberg, Jens U. Balfour, Gail F. Lee, Y. Chen Liddy, Helen Irving, Diane Sheldon, Joanna Slack, Mary P. E. Pollard, Andrew J. Heath, Paul I. St Georges Univ London London England Univ Oxford Oxford OX1 2JD England St George Hosp London England Hlth Protect Agcy Ctr Infect London England

An increase in Haemophilus influenzae type b (Hib) in British children has been linked to the widespread use of a diphtheria/tetanus/acellular pertussis combination vaccine (DTaP-Hib). We measured anti-polyribosyl-ribitol phosphate antibody concentration and avidity before and after a Hib booster in 176 children 2-4 years of age who had received 3 doses of DTP-Hib (either DT whole cell pertussis-Hib or DTaP-Hib) combination vaccine in infancy. We also measured pharyngeal carriage of Hib. Antibody concentrations before and avidity indices after vaccination were low (geometric mean concentration 0.46 mu g/mL, 95% confidence interval [CI] 0.36-0.58;geometric mean avidity index 0.16, 95% Cl 0.14-0.18) and inversely related to the number of previous doses of DTaP-Hib (p = 0.02 and p < 0.001, respectively). Hib was found in 2.1% (95% Cl 0.7%-6.0%) of study participants. Our data support an association between DTaP-Hib vaccine combinations and clinical Hib disease through an effect on antibody concentration and avidity.

关键词： .St George children years booster carriage reemergence pharyngeal Haemophilus influenzae type Hib disease influenzae type Hib pertussis combination antibody concentration DTP-Hib Hib Antibody geometric mean avidity doses of DTaP-Hib

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Morphology and development of the human vocal tract: A study using magnetic resonance imaging

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JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA 1999年第3期106卷 1511-1522页

作者： Fitch, WT Giedd, J Harvard Univ MIT Speech & Hearing Sci Program Cambridge MA 02138 USA NIMH Child Psychiat Branch Bethesda MD 20892 USA

Magnetic resonance imaging was used to quantify the vocal tract morphology of 129 normal humans, aged 2-25 years. Morphometric data, including midsagittal vocal tract length, shape, and proportions, were collected using computer graphic techniques. There was a significant positive correlation between vocal tract length and body size (either height or weight). The data also reveal clear differences in male and female vocal tract morphology, including changes in overall vocal tract length and the relative proportions of the oral and pharyngeal cavity. These sex differences are not evident in children, but arise at puberty, suggesting that they are part Of the vocal remodeling process that occurs during puberty in males. These findings have implications for speech recognition, speech forensics, and the evolution of the human speech production system, and. provide a nonnative standard for future studies of human vocal tract morphology and development. (C) 1999 Acoustical Society of America. [S0001-4966(99)02008-1].

关键词： .positive correlation midsagittal pharyngeal human vocal vocal tract morphology vocal tract length length and body

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Cephalometric pharyngeal Morphology in Adults with Unoperated Cleft Palate

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CLEFT PALATE CRANIOFACIAL JOURNAL 2024年

作者： Cao, Congcong Li, Deren Gong, Hanwen Zheng, Qian Xu, Chao Shi, Bing Shandong Second Med Univ Weifang Hosp Tradit Chinese Med Dept Oral & Maxillofacial Surg Weifang Peoples R China Sichuan Univ West China Hosp Stomatol Dept Oral & Maxillofacial Surg Chengdu 610041 Peoples R China Shandong Oriental Solut Engn Technol Dept Syst Integrat Weifang Peoples R China

Objective The aim of this study was to cephalometrically evaluate the pharyngeal morphology in adults with unoperated Submucous Cleft Palate (SMCP), adults with unoperated Overt Cleft Palate (OCP), and adults without *** This study employed a retrospective cross-sectional design. Lateral cephalometric radiography was performed on three groups of adults: 1) 29 with unrepaired SMCP;2) 41 with unrepaired OCP;and 3) 39 without clefts, who served as controls. One-way ANOVA and rank-sum tests were used for intergroup comparisons. P value was set at .*** The soft palate length and the ratio of soft palate length to pharyngeal depth were significantly lower in subjects with unoperated SMCP and OCP than in non-cleft controls. Significant differences were also observed in pharyngeal depth, nasopharyngeal depth, and posterior pharyngeal wall thickness between subjects with unoperated OCP and non-cleft *** pharyngeal morphology differs significantly between individuals with and without clefts, particularly in soft palate length and the ratio of soft palate length to pharyngeal depth.

关键词： submucous cleft palate overt cleft palate pharyngeal cephalometry soft palate

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Epidemiology and molecular identification of mycoplasma pneumoniae associated with respiratory infections in Zhejiang province, China, 2008-2017

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JOURNAL OF CLINICAL LABORATORY ANALYSIS 2020年第11期34卷 e23460-e23460页

作者： Jiang, Qian Yang, Fangfang Peng, Yumeng Dong, XiaoYan Ge, Yumei Hangzhou Med Coll Peoples Hosp Dept Clin Lab Zhejiang Prov Peoples Hosp 158 Shangtang Rd Hangzhou 310014 Peoples R China Univ Chinese Acad Sci Dept Lab Ctr Huamei Hosp Ningbo Hosp 2 Ningbo Peoples R China Wenzhou Med Univ Sch Lab Med & Life Sci Wenzhou Peoples R China Bengbu Med Coll Bengbu Peoples R China Zhejiang Chinese Med Univ Med Coll 2 Hangzhou Peoples R China

Introduction Mycoplasma pneumoniae is a common cause of respiratory infections in humans. The aim of this study was to investigate the infection of Mycoplasma pneumoniae (MP) in patients with acute respiratory tract infections in Zhejiang Province from 2008 to 2017, and to provide evidence for the early diagnosis and prevention of MP pneumonia. Methods MP-DNA was detected in nasopharyngeal swabs of patients with acute respiratory tract infection by real-time fluorescent PCR (TaqMan probe). Statistical analysis and epidemiological investigation were carried out on the test results. Results There were 10 296 patients with acute respiratory tract infection in Zhejiang Provincial People's Hospital from 2008 to 2017, including 4387 females and 5909 males. A total of 1251 MP-DNA-positive patients were detected, with a total positive rate of 12.2% (1251/10296). Among 1251 patients with MP infection, 571 were female positive, with an average positive rate of 13.0% (571/4387), and 680 were male positive, with a positive rate of 11.5% (680/5909). From 2008 to 2017, the positive rates were 22.8% (33 cases), 20.9% (211 cases), 20.9% (350 cases), 5.5% (70 cases), 11.7% (136 cases), 15.2% (190 cases), 7.8% (94 cases), 5.9% (62 cases), 7.8% (56 cases), and 6.0% (49 cases), respectively. Of 1251 MP-DNA-positive patients, 1243 (99.4%) were younger than 18 years old. Conclusions Mycoplasma pneumoniae infection mainly occurs from late summer to autumn and in the age below 18 years, suggesting that early diagnosis and prevention of MP infection in adolescents should be emphasized.

关键词： acute respiratory infection fluorescent PCR Mycoplasma pneumoniae pharyngeal swab

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pharyngeal Aspiration of Complete Upper Denture in 90-Year-Old Man; a Case Report

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Emergency (Tehran, Iran) 2015年第3期3卷 117-9页

作者： Mehrdad Haghighi Simin Dokht Shoaei Clinical Research and Development Center Imam Hossein Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.

Foreign body aspiration is unusual in adults, except those who are debilitated or have neuropsychiatric disorders. It can be a life-threatening situation and it often requires a high index of suspicion, because the diagnosis can be obscure. Prompt diagnosis and intervention through foreign body retrieval are critical to prevent significant morbidity and mortality. We present a case of denture aspiration by a debilitated 90 years old man. He had aspirated his complete upper denture to pharynx causing incomplete obstruction with pleasure whistling respiratory sound, dyspnea, dysphagia and dysphonia. He underwent successful retrieval of the dental plate manually by fingers with complete resolution of symptoms.

关键词： pharyngeal aspiration case report foreign body

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The Effects of Neuromuscular Electrical Stimulation on pharyngeal Transit Time

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JOURNAL OF PHYSICAL THERAPY SCIENCE 2013年第7期25卷 849-851页

作者： Kim, Seon-Rye Kwon, Ki-Hyun Cho, Byung-Jun Chungnam Natl Univ Dept Publ Hlth Taejon South Korea Soonchunhyang Univ Chunan Hosp Occupat Therapy Sect Asan Chungnam South Korea Kangwon Natl Univ Dept Emergency Med Technol Samchuock City 245711 Kangwondo South Korea

[Purpose] The purpose of this study was to identify the effects of Neuromuscular Electrical Stimulation (NMES) on pharyngeal transit time. [Subjects] Subjects were divided into normal old persons aged over 70 (N=18), and normal young persons aged under 30 (N=10). [Method] We measured the pharyngeal Transit Time (PTT) to determine their swallowing characteristics. NMES was used to stimulate old group's suprahyoid and infrahyoid muscles 60 minutes a day, 5 days a week for 2 weeks using four electrodes. We used SPSS version 14.0 to analyze and compare the data between the 2 groups. [Results] After NMES, PTT of the normal old group became significantly shorter. PTT was much shorter, but was still longer than that of the normal young group. [Conclusion] The PTTs of the two groups classified by age were significantly different.

关键词： pharyngeal Video fluoroscopy Electrical stimulation

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The IMAP flap for pharygoesophageal reconstruction following stricture release

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JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY 2012年第6期65卷 810-813页

作者： Shayan, R. Syme, D. Y. Grinsell, D. Univ Melbourne Royal Melbourne Hosp Reconstruct Plast Surg Res Unit Dept Surg Parkville Vic 3050 Australia Univ Melbourne Dept Anat & Cell Biol Jack Brockhoff Reconstruct Plast Surg Res Unit Parkville Vic 3050 Australia St Vincents Hosp Melbourne Dept Plast Surg Fitzroy Vic 3065 Australia Peter MacCallum Canc Ctr Angiogenesis Lab Melbourne Vic 3002 Australia

Small-medium pharyngo-oesophageal or peri-tracheostoma defects represent a difficult reconstructive problem. Previous solutions included locoregional options such as the deltopectoral flap, or microvascular free tissue transfer. The authors present a novel application of the internal mammary artery perforator (IMAP) flap for reconstructing such defects. The IMAP flap may be mapped using pre-operative Doppler or CTA, and is raised on a single perforator. The relatively quick and simple flap raise provides robust fasciocutaneous tissue, may be tunneled subcutaneously to reach the neck and yields an inconspicuous donor site. The authors provide several cases demonstrating applications of the IMAP flap for reconstructing small-medium sized defects following release of annular pharyngoesophageal stricture, and studies documenting post-operative swallow. Overall, the pedicled IMAP fasciocutaneous flap is a useful technique to provide excellent composite tissue to reconstruct defects resulting from release of annular pharyngeal strictures. It is technically simple, and yields an inconspicuous anterior chest donor site. (C) 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

关键词： Reconstruction pharyngeal Perforator Flap Stricture Perforasome

来源： ClinicalKey（临床精钥... SCIE

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