Predictive value of image indexes of B-mode and power Doppler sonography on the efficacy of high intensity focused ultrasound ablation for uterine fibroids

作者全名："Chen, Xiaohui; Huang, Guohua; Zhang, Lian; Bai, Jin"

作者地址："[Chen, Xiaohui; Zhang, Lian; Bai, Jin] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing Key Lab Biomed Engn, Chongqing 400016, Peoples R China; [Huang, Guohua] Suining Cent Hosp, Dept Gynecol, Suining, Sichuan, Peoples R China"

通信作者："Zhang, L; Bai, J (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing Key Lab Biomed Engn, Chongqing 400016, Peoples R China."

来源：INTERNATIONAL JOURNAL OF HYPERTHERMIA

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000805395700001

JCR分区：Q2

影响因子：3.1

年份：2022

卷号：39

期号：1

开始页：772

结束页：779

文献类型：Article

关键词：High intensity focused ultrasound (HIFU); fibroids; transvaginal ultrasonography; MRI signal intensity; ultrasound image indexes

摘要："Objective To investigate the value of the image indexes of B-mode and power Doppler sonography in predicting the therapeutic efficacy of high intensity focused ultrasound (HIFU) ablation for uterine fibroids. Materials and methods Two hundred and three patients with a solitary uterine fibroid were enrolled in this study. Every patient underwent transvaginal sonography (TVS) and magnetic resonance imaging (MRI) before HIFU. The patients were divided into hypointense, isointense and hyperintense fibroid groups based on T2 weighted MR imaging characteristics, and ultrasonic image indexes of the fibroids in different groups were compared. Multiple linear regression analysis was used to evaluate the correlation between ultrasonic image indexes and energy efficiency factor (EEF), non-perfused volume (NPV) ratio of uterine fibroids. Results Among them, 72 patients had a hypointense fibroid, 70 had an isointense fibroid and 61 had a hyperintense fibroid. Significant differences were observed in the ultrasound imaging gray scale value difference between the myometrium and uterine fibroids (GSmyo-fib), the ultrasound imaging gray scale value ratio of fibroids over the myometrium (GSfib/myo), and the ratio of power Doppler pixel area to fibroid area (PDPA/FA) among the three groups (p < 0.05). Linear regression analysis showed that the PDPA/FA and the location of fibroids were the factors affecting the NPV ratio, a model for predicting the NPV ratio was established. Conclusions A model with the PDPA/FA for NPV ratio could be used to predict the therapeutic efficacy of HIFU for fibroids."

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