Four-year experience with more than 1000 cases of total laparoscopic liver resection in a single center

作者全名："Lan, Xiang; Zhang, Hai-Li; Zhang, Hua; Peng, Yu-Fu; Liu, Fei; Li, Bo; Wei, Yong-Gang"

作者地址："[Lan, Xiang] Chongqing Med Univ, Affiliated Hosp 1, Dept Hepatobiliary Surg, Chongqing 400016, Peoples R China; [Zhang, Hai-Li; Zhang, Hua; Peng, Yu-Fu; Liu, Fei; Li, Bo; Wei, Yong-Gang] Sichuan Univ, Dept Liver Surg, West China Hosp, Chengdu 610041, Sichuan, Peoples R China; [Zhang, Hai-Li; Zhang, Hua; Peng, Yu-Fu; Liu, Fei; Li, Bo; Wei, Yong-Gang] Sichuan Univ, Liver Transplantat Ctr, West China Hosp, Chengdu 610041, Sichuan, Peoples R China; [Wei, Yong-Gang] Sichuan Univ, West China Hosp, Dept Liver Surg, 37 Guo Xue Rd, Chengdu 610041, Sichuan, Peoples R China; [Wei, Yong-Gang] Sichuan Univ, West China Hosp, Liver Transplantat Ctr, 37 Guo Xue Rd, Chengdu 610041, Sichuan, Peoples R China"

通信作者："Wei, YG (通讯作者)，Sichuan Univ, West China Hosp, Dept Liver Surg, 37 Guo Xue Rd, Chengdu 610041, Sichuan, Peoples R China.; Wei, YG (通讯作者)，Sichuan Univ, West China Hosp, Liver Transplantat Ctr, 37 Guo Xue Rd, Chengdu 610041, Sichuan, Peoples R China."

来源：WORLD JOURNAL OF GASTROENTEROLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000828187100014

JCR分区：Q2

影响因子：4.3

年份：2022

卷号：28

期号：25

开始页：2968

结束页：2980

文献类型：Article

关键词：Laparoscopic liver resection; Single-center experience; Learning curve; Liver

摘要："BACKGROUND Laparoscopic liver resection (LLR) has become a safe surgical procedure that needs additional summarization. AIM To review 4 years of total LLR surgeries, exceeding 1000 cases, which were performed at a single center. METHODS Patients who underwent LLR at West China Hospital of Sichuan University between January 2015 and December 2018 were identified. Surgical details, including the interventional year, category of liver disease, and malignant liver tumors prognosis, were evaluated. The learning curve for LLR was evaluated using the cumulative sum method. The Kaplan-Meier method was used to perform survival analysis. RESULTS Ultimately, 1098 patients were identified. Hepatocellular carcinoma (HCC) was the most common disease that led to the need for LLR at the center (n = 462, 42.08%). The average operation time was 216.94 +/- 98.51 min. The conversion rate was 1.82% (20/1098). The complication rate was 9.20% (from grade II to V). The 1-year and 3-year overall survival rates of HCC patients were 89.7% and 81.9%, respectively. The learning curve was grouped into two phases for local resection (cases 1-106 and 107-373), three phases for anatomical segmentectomy (cases 1-44, 45-74 and 75-120), and three phases for hemihepatectomy (cases 1-17, 18-48 and 49-88). CONCLUSION LLR may be considered a first-line surgical intervention for liver resection that can be performed safely for a variety of primary, secondary, and recurrent liver tumors and for benign diseases once technical competence is proficiently attained."

基金机构：Sichuan Provincial Key Project-Science and Technology Project Plan [2019yfs0372]

基金资助正文："Supported by Sichuan Provincial Key Project-Science and Technology Project Plan, No. 2019yfs0372."