Factors Influencing Men's Attitudes toward HPV Vaccination in Males Included in the Chinese National Immunization Program

作者全名："Tao, Yi; Shao, Huarui; Zhang, Ting; Pu, Junliang; Tang, Chengyong"

作者地址："[Tao, Yi; Pu, Junliang; Tang, Chengyong] Chongqing Med Univ, Dept Phase & Clin Trial Ward, Affiliated Hosp 1, Chongqing 400016, Peoples R China; [Shao, Huarui] Chongqing Med Univ, Coll Pharm, Chongqing 400016, Peoples R China; [Zhang, Ting] Chongqing Med Univ, Clin Coll 1, Chongqing 400016, Peoples R China"

通信作者："Tang, CY (通讯作者)，Chongqing Med Univ, Dept Phase & Clin Trial Ward, Affiliated Hosp 1, Chongqing 400016, Peoples R China."

来源：VACCINES

ESI学科分类：IMMUNOLOGY

WOS号：WOS:000832400200001

JCR分区：Q1

影响因子：7.8

年份：2022

卷号：10

期号：7

开始页：　

结束页：　

文献类型：Article

关键词：human papillomavirus; vaccination; HPV vaccine in males; factors influencing vaccination; national immunization programs

摘要："Background: Human papillomavirus (HPV) infection is the most common sexually transmitted disease, and it is associated with anogenital warts and oropharyngeal and anogenital cancers. Among female malignant tumors in China, the incidence of cervical cancer ranks second, with only breast cancer being more prevalent. HPV infection and related diseases affects both women and men. HPV vaccination is an optimal prevention strategy in preventing HPV infection and related diseases. The inclusion of the HPV vaccine in the national immunization program is an effective way to increase immunization coverage, reduce the burden of HPV related diseases, and increase national life expectancy. Objective: This study aimed to explore the factors influencing the attitudes of Chinese men toward the inclusion of the HPV vaccine in males included in the national immunization program, thus providing reference for launching the national immunization program policy. Methods: We invited men aged 20 to 45 to participate in an online survey. The participants were requested to complete a questionnaire, including sociodemographic characteristics, sexual behavior characteristics, knowledge of HPV and the HPV vaccine, and attitudes toward the HPV vaccine. A logistic regression model was constructed to analyze the influencing factors of attitudes. Results: A total of 660 males in China participated in this survey, and 80.45% supported the inclusion of HPV vaccines in national immunization programs. Participants earning CNY 100,000-200,000 (dds ratio (OR): 0.63, 95% confidence interval (CI): 0.39-1.00) or >= 200,000 (OR: 0.34, 95% CI: 0.17-0.68) were more likely to disapprove this strategy. Compared with people without a history of HPV infection, those with a history of HPV infection (OR: 1.84, 95% CI: 1.17-2.90) were more likely to approve. Men who had better knowledge of HPV were more likely to approve than men with less knowledge about HPV (OR: 1.44, 95% CI: 1.17-1.79). Compared with participants who did not know when the HPV vaccine should be given, those who knew that the ideal time of vaccination is before an individual becomes sexually active (OR: 1.75, 95% CI: 1.04-2.95) were more likely to approve. Conclusion: One in five men did not support the inclusion of HPV vaccines in national immunization programs, and they are likely to be from higher socioeconomic background and have poor knowledge of HPV. In order to implement comprehensive immunity, targeted actions need to be taken at national and public levels. In addition, when implementing measures, more attention needs to be paid to lower income men, men without a history of HPV infection and with poor knowledge of HPV, as well as young men."

基金机构："Science and Technology Commission Foundation of Chongqing, China [cstc2019jscx-gksbX0005, cstc2020jscx-msxmX0090]; Science and Technology Commission & Health Commission Joint Research Project [2020GDRC022]"

基金资助正文："This research was funded by the Science and Technology Commission Foundation of Chongqing, China (No. cstc2019jscx-gksbX0005, cstc2020jscx-msxmX0090) and the Science and Technology Commission & Health Commission Joint Research Project (No. 2020GDRC022)."