Solitary fibrous tumors in prostate: a case report with review of the literature

作者全名："Peng, Yueqiang; Jiang, Yu; Ding, Siwei; Zheng, Yongbo; Tang, Wei; Liu, Jiayu"

作者地址："[Peng, Yueqiang; Jiang, Yu; Ding, Siwei; Zheng, Yongbo; Tang, Wei; Liu, Jiayu] Chongqing Med Univ, Dept Urol, Affiliated Hosp 1, Chongqing 400016, Peoples R China"

通信作者："Liu, JY (通讯作者)，Chongqing Med Univ, Dept Urol, Affiliated Hosp 1, Chongqing 400016, Peoples R China.; Tang, W (通讯作者)，1 Yixueyuan Rd, Yuzhong Dist, Peoples R China."

来源：AGING MALE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000842371300001

JCR分区：Q3

影响因子：2.6

年份：2022

卷号：25

期号：1

开始页：219

结束页：227

文献类型：Review

关键词：Solitary fibrous tumor; prostate; case report; immunohistochemistry; STAT-6

摘要："Background Solitary fibrous tumor (SFT) is a relatively rare type of mesenchymal neoplasm that occurs most frequently in the pleura. However, SFT originating from the prostate is particularly uncommon and only approximately 39 cases were reported before. Herein, we reported a rare case of a patient diagnosed with prostate SFT and presented a literature review. Case presentation: A 50-year-old Asian with irritative urinary symptoms was admitted to our hospital and almost all the evidence indicated that benign prostate hyperplasia (BPH) caused his symptoms. Therefore, transurethral resection of the prostate (TURP) was performed, but histopathological and Immunohistochemical (IHC) assessments showed that spindle cells arranged disorderly in the TURP specimen with a cluster of differentiation 34 (CD34), B-cell lymphoma-2 (Bcl-2), and signal transducer and activator of transcription 6 (STAT6) highly expressed and SFT was diagnosed. Finally, the patient underwent a radical prostatectomy and there was no disease progression observed thereafter. Conclusions Prostate SFT is extremely rare, and to our knowledge, this is the first case of prostate SFT that is difficult to differentiate from small volume BPH. IHC examinations are of great diagnostic value. Radical resection of the tumor appears to be the most effective method at present and continuous follow-up is highly recommended."

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