"Recent advances and future prospects of the potential-resolved strategy in ratiometric, multiplex, and multicolor electrochemiluminescence analysis"

作者全名："Wang, Shijun; Zhu, Shu; Kang, Ziqi; Chen, Yidan; Liu, Xiancheng; Deng, Zixin; Hu, Kun; Wang, Guixue; Zhang, Yuchan; Zang, Guangchao"

作者地址："[Wang, Shijun; Zhu, Shu; Kang, Ziqi; Deng, Zixin; Hu, Kun; Zhang, Yuchan; Zang, Guangchao] Chongqing Med Univ, Inst Life Sci, Chongqing 400016, Peoples R China; [Wang, Shijun; Zhu, Shu; Kang, Ziqi; Deng, Zixin; Hu, Kun; Zang, Guangchao] Chongqing Med Univ, Lab Tissue & Cell Biol, Lab Teaching & Management Ctr, Chongqing 400016, Peoples R China; [Chen, Yidan; Liu, Xiancheng; Wang, Guixue] Chongqing Univ, Key Lab Biorheol Sci & Technol, State & Local Joint Engn Lab Vasc Implants, Bioengn Coll,Minist Educ, Chongqing 400030, Peoples R China; [Wang, Guixue; Zang, Guangchao] Jinfeng Lab, Chongqing 401329, Peoples R China"

通信作者："Zhang, YC; Zang, GC (通讯作者)，Chongqing Med Univ, Inst Life Sci, Chongqing 400016, Peoples R China.; Zang, GC (通讯作者)，Chongqing Med Univ, Lab Tissue & Cell Biol, Lab Teaching & Management Ctr, Chongqing 400016, Peoples R China.; Wang, GX (通讯作者)，Chongqing Univ, Key Lab Biorheol Sci & Technol, State & Local Joint Engn Lab Vasc Implants, Bioengn Coll,Minist Educ, Chongqing 400030, Peoples R China.; Wang, GX; Zang, GC (通讯作者)，Jinfeng Lab, Chongqing 401329, Peoples R China."

来源：THERANOSTICS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000862815900003

JCR分区：Q1

影响因子：12.4

年份：2022

卷号：12

期号：15

开始页：6779

结束页：6808

文献类型：Review

关键词：electrochemiluminescence; potential-resolved strategy; ratiometric electrochemiluminescence sensors; multiplex electrochemiluminescence sensors; multicolor electrochemiluminescence sensors

摘要："The potential-resolved strategy has gradually demonstrated its distinct values in electro-chemiluminescence (ECL) bio-sensing due to its superior characteristics, such as low instrument requirement, short assay time, and improved sample throughput, in conjunction with spatial-and spectrum-resolved techniques. It has recently been widely generalized into versatile multiple-signal ECL analytic platforms, especially in ratiometric and multiplex ECL sensors, in accordance with some specific principles. Furthermore, luminophore pairs with potential-and wavelength-resolved properties have been utilized to visualize biosensors that display multiple colors depending on analyte concentration. However, only a few comprehensive reports on the principles, construction, and application of various ECL sensors in potential-resolved schemes have been published. This review aims to recount the potential-resolved strategy applying to (a) ratiometric ECL sensors, (b) multiplex ECL sensors, and (c) multicolor ECL sensors and to discuss the distinctions and connections among the application principles of these strategies. Finally, the future prospects of ECL-based potential-resolved analysis are explored."

基金机构："Natural Science Foundation of Chongqing [cstc2020jcyj-msxmX0330, cstc2021jsyj-yzysbA0057]; National Natural Science Foundation of China [31971242, 12032007]; Chongqing Science, the Technology Bureau [cstc2019jcyj-zdxmX0028, cstc2020jscx-msxmX0132]; Project of Tutorial System of Medical Undergraduate in Lab Teaching & Management Center in Chongqing Medical University [LTMCMTS202005]; JinFeng Laboratory Foundation, Chongqing, China [jfkyjf202203001]"

基金资助正文："This work was supported by the grants from the Natural Science Foundation of Chongqing (cstc2020jcyj-msxmX0330, cstc2021jsyj-yzysbA0057); the National Natural Science Foundation of China (31971242, 12032007); the Chongqing Science, the Technology Bureau (cstc2019jcyj-zdxmX0028, cstc2020jscx-msxmX0132); the Project of Tutorial System of Medical Undergraduate in Lab Teaching & Management Center in Chongqing Medical University (LTMCMTS202005) and the JinFeng Laboratory Foundation, Chongqing, China (jfkyjf202203001)."