Case Report Partial hydatidiform mole pregnancy ended in full-term delivery of a normal infant: a case presentation

作者全名："Qu, Qing-Hua; Lin, Yi; Feng, Xue; Hao, Li -Juan"

作者地址："[Qu, Qing-Hua; Lin, Yi; Feng, Xue; Hao, Li -Juan] Chongqing Med Univ, Women & Childrens Hosp, Chongqing Hlth Ctr Women & Children, Dept Obstet & Gynecol, Chongqing 401147, Peoples R China"

通信作者："Hao, LJ (通讯作者)，Chongqing Med Univ, Women & Childrens Hosp, Chongqing Hlth Ctr Women & Children, Dept Obstet & Gynecol, Chongqing 401147, Peoples R China."

来源：AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH

ESI学科分类：BIOLOGY & BIOCHEMISTRY

WOS号：WOS:000862829300031

JCR分区：Q4

影响因子：2.2

年份：2022

卷号：14

期号：8

开始页：5740

结束页：5745

文献类型：Article

关键词：Partial hydatidiform mole; prenatal diagnosis; normal live fetus; case presentation

摘要："Background: Twin pregnancy with a partial hydatidiform mole (PHM) and a coexistent live fetus is extremely rare. The fetus usually has a normal karyotype. The surviving rate of the fetus till lung maturity is only about 25-40%. PHM pregnancy almost ends in abortion due to the presence of triploid embryo. Here, we report a case of PHM coexistent with a live fetus resulting in a live baby. Case presentation: A PHM pregnancy was diagnosed by ultrasonography in a 28-year-old Chinese woman, with normal fetal morphology and mosaicism as indicated by amniocentesis. After being fully informed of the risks, the woman chose to proceed with the pregnancy and finally gave birth to a baby girl and the infant was delivered at term. A single placenta with vesicular changes and peripheral blood diploid chromosomes were observed. There were no serious maternal complications. In conclusion, the diagnosis, management, and monitoring of this condition, which is very rare in clinical practice, remain challenging. Under proper management, a PHM-combined pregnancy can still end in full-term delivery of a normal living fetus."

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