Facile construction of dibenzodioxo[3.3.1]nonanes bearing spirocyclohexadienones via domino [4+2] cycloaddition/C(sp(3))-H oxidative dehydrogenation coupling reactions

作者全名:"Chen, Genhui; Li, Hongjiao; Liang, Guojuan; Pu, Qian; Bai, Lijuan; Zhang, Dexin; Ye, Ying; Li, Yong; Zhou, Jing; Zhou, Hui"

作者地址:"[Chen, Genhui; Li, Hongjiao; Liang, Guojuan; Pu, Qian; Bai, Lijuan; Zhang, Dexin; Ye, Ying; Zhou, Jing; Zhou, Hui] Chongqing Med Univ, Coll Pharm, Chongqing Res Ctr Pharmaceut Engn, Chongqing 400016, Peoples R China; [Li, Yong] Chongqing Univ Arts & Sci, Coll Pharm, Natl & Local Joint Engn Res Ctr Targeted & Innovat, IATTI, Chongqing 402160, Peoples R China"

通信作者:"Zhou, J; Zhou, H (通讯作者),Chongqing Med Univ, Coll Pharm, Chongqing Res Ctr Pharmaceut Engn, Chongqing 400016, Peoples R China."

来源:ORGANIC & BIOMOLECULAR CHEMISTRY

ESI学科分类:BIOLOGY & BIOCHEMISTRY

WOS号:WOS:000886380100001

JCR分区:Q1

影响因子:3.2

年份:2022

卷号: 

期号: 

开始页: 

结束页: 

文献类型:Article; Early Access

关键词: 

摘要:A novel palladium catalyzed homodimerization of ortho-hydroxyphenyl substituted p-QMs has been developed via [4 + 2] cycloaddition/oxidative dehydrogenation coupling domino reactions. An interesting palladium catalyzed intramolecular benzyl C-H oxidation dehydrogenation to form a transannular C(sp(3))-O bond was found. This protocol provided an efficient method to construct various dibenzodioxo[3.3.1]nonanes bearing spirocyclohexadienones.

基金机构:National Natural Science Foundation of China; Science and Technology Planning Project of Yuzhong District of Chongqing City; Project of the School of Pharmacy of Chongqing Medical University; [21672031]; [20190128]; [YXY2021XSGG01]

基金资助正文:"The work is supported by the National Natural Science Foundation of China (21672031), the Science and Technology Planning Project of Yuzhong District of Chongqing City (No. 20190128), and the Project of the School of Pharmacy of Chongqing Medical University (YXY2021XSGG01)."