Efficiency and safety of quadratus lumborum block in percutaneous nephrolithotomy: a meta-analysis of randomized controlled studies

作者全名："Zheng, Changjian; Yang, Hongmei; Yang, Lin; Lv, Yalan; Li, Yu; Luo, Jun; Xiong, Bo"

作者地址："[Zheng, Changjian; Yang, Lin; Luo, Jun; Xiong, Bo] Chongqing Med Univ, Dept Urol, Bishan Hosp, Chongqing 402760, Peoples R China; [Yang, Hongmei] Chongqing Med Univ, Dept Rehabil, Bishan Hosp, Chongqing 402760, Peoples R China; [Lv, Yalan] Chongqing Med Univ, Dept Sch Med Informat, Chongqing 400016, Peoples R China; [Li, Yu] Peoples Hosp Rongchang Dist, Dept Crit Care Med, Chongqing 402460, Peoples R China"

通信作者："Zheng, CJ (通讯作者)，Chongqing Med Univ, Dept Urol, Bishan Hosp, Chongqing 402760, Peoples R China."

来源：UROLITHIASIS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000900033700001

JCR分区：Q2

影响因子：3.1

年份：2022

卷号：51

期号：1

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结束页：　

文献类型：Review

关键词：Percutaneous nephrolithotomy; Quadratus lumborum block; Meta-analysis

摘要："To evaluate the effect of quadratus lumborum block (QLB) for postoperative analgesia after percutaneous nephrolithotomy (PCNL), we searched Pubmed, Embase, Cochrane library, the Chinese Biomedical Literature Database, and randomized controlled trials (RCTs) assessing analgesic efficacy of QLB for PCNL are included in this meta-analysis. The related trials met the inclusion criteria were analyzed using RevMan 5.4 software, the weighted mean difference (WMD), with their corresponding 95% CI, was calculated to compare continuous variables. Nine RCTs are included in the meta-analysis showed that QLB group had significantly lower opioids consumption (WMD - 29.59 95% CI - 43.64 to - 15.55; P < 0.00001), lessen visual analog scale (VAS) after surgery 2 h (WMD - 1.35, 95% CI - 1.93 to - 0.76; P < 0.00001), 6 h (WMD - 1.47, 95% CI - 2.04 to - 0.91; P < 0.00001) 12 h (WMD - 1.75, 95% CI - 3.17 to - 0.32; P = 0.02) and 24 h (WMD - 1.4, 95% CI - 1.86 to - 0.94; P < 0.00001), shorter hospital stay(WMD - 0.7, 95% CI -1.26 to - 0.14, P < 0.00001) and reduce intestinal exhaust recovery time (WMD - 7.41, 95% CI - 9.36 to - 5.46, P < 0.00001) than in the control group. QLB offers some potential advantages in terms of opioids consumption, VAS, hospital stay and intestinal exhaust recovery time. However, good quality and large studies with long-term follow-up are warranted for further research."

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