Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database

作者全名："Zheng, Zheng; Xie, Yangli; Huang, Junlan; Sun, Xianding; Zhang, Ruobin; Chen, Lin"

作者地址："[Zheng, Zheng; Xie, Yangli; Huang, Junlan; Zhang, Ruobin; Chen, Lin] Army Med Univ, Daping Hosp, Res Inst Surg, Ctr Bone Metab & Repair,Trauma Ctr,State Key Lab T, Chongqing, Peoples R China; [Zheng, Zheng] Fujian Med Univ, Xiamen Univ, Hosp Joint Logist Support Force 900, Dongfang Hosp,Fuzong Clin Coll,Dept Emergency, Fuzhou, Fujian, Peoples R China; [Sun, Xianding] Chongqing Med Univ, Affiliated Hosp 2, Dept Orthopaed, Chongqing, Peoples R China"

通信作者："Chen, L (通讯作者)，Army Med Univ, Daping Hosp, Res Inst Surg, Ctr Bone Metab & Repair,Trauma Ctr,State Key Lab T, Chongqing, Peoples R China."

来源：BMJ OPEN

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000901531900028

JCR分区：Q2

影响因子：2.9

年份：2022

卷号：12

期号：12

开始页：　

结束页：　

文献类型：Article

关键词：EPIDEMIOLOGY; Hypertension; DIABETES & ENDOCRINOLOGY

摘要："ObjectiveTo explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.DesignA cross-sectional study.SettingNational Health and Nutrition Examination Surveys database.Participants12 576 patients.Primary and secondary outcome measuresThe prevalence and patterns of multimorbidity.ResultsHigh cholesterol had the highest prevalence in all population (33.4 (95% CI: 32.0 to 34.9)) and males. In females <65 years, the most prevalent disease was sleep disorder (32.1 (95% CI: 29.6 to 34.5)) while in females >= 65 years, hypertension was the most prevalent disease (63.9 (95% CI: 59.9 to 67.9)). Hypertension and high cholesterol were associated with the highest support (occur together most frequently) in all population regardless of genders. Hypertension displayed the highest betweenness centrality (mediating role in the network) followed by high cholesterol and arthritis in all population. For males aged <65 years, hypertension and high cholesterol presented the highest betweenness centrality. In males >= 65 years, hypertension, high cholesterol and arthritis were the top three diseases of degree centrality (direct association with other conditions). As for females >= 65 years, hypertension showed the highest betweenness centrality followed by high cholesterol and arthritis. The associations of hypertension, arthritis and one other item with high cholesterol presented the highest support in all population. In males, the associations of depression, hypertension with sleep disorders had the highest lift (the chance of co-occurrence of the conditions and significant association). Among females, the associations of depression, arthritis with sleep disorders had the highest lift.ConclusionHypertension and high cholesterol were prevalent in all population, regardless of females and males. Hypertension and high cholesterol, arthritis and hypertension, and diabetes and hypertension were more likely to coexist. The findings of this study might help make plans for the management and primary care of people with one or more diseases."

基金机构："National Key Research and Development Program of China [2018YFA0800802]; National Natural Science Foundation of China [81830075, 82122044, 81772306, 81721001]; Key research and development projects of science and technology innovation of social undertakings and people's livelihood security in Chongqing [cstc2017shms-zdyfX0027]"

基金资助正文："This work is supported by research funding from the National Key Research and Development Program of China (2018YFA0800802), the National Natural Science Foundation of China (No. 81830075, 82122044, 81772306, 81721001) and Key research and development projects of science and technology innovation of social undertakings and people's livelihood security in Chongqing (cstc2017shms-zdyfX0027)"