Follow-up study of depressive state on patients with atrial fibrillation 1 year after radio-frequency ablation

作者全名："Ren, Lei; Li, Wenjun; Su, Xin; Yang, Yangyang; Zhang, Yuanzhuo; Liu, Xiaozhu; Hu, Guangquan; Ning, Bin"

作者地址："[Ren, Lei; Li, Wenjun; Su, Xin; Ning, Bin] Anhui Med Univ, Dept Cardiovasc Med, Fuyang Peoples Hosp, Fuyang, Peoples R China; [Yang, Yangyang; Zhang, Yuanzhuo] Bengbu Med Coll, Dept Cardiovasc Med, Fuyang Hosp, Fuyang, Peoples R China; [Liu, Xiaozhu] Chongqing Med Univ, Dept Cardiovasc Med, Affiliated Hosp 2, Chongqing, Peoples R China; [Hu, Guangquan] Anhui Med Univ, Dept Cardiovasc Med, Affiliated Hosp 2, Hefei, Peoples R China"

通信作者："Ning, B (通讯作者)，Anhui Med Univ, Dept Cardiovasc Med, Fuyang Peoples Hosp, Fuyang, Peoples R China.; Hu, GQ (通讯作者)，Anhui Med Univ, Dept Cardiovasc Med, Affiliated Hosp 2, Hefei, Peoples R China."

来源：FRONTIERS IN PSYCHIATRY

ESI学科分类：PSYCHIATRY/PSYCHOLOGY

WOS号：WOS:000907325700001

JCR分区：Q2

影响因子：4.7

年份：2022

卷号：13

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：SDS; depression; AF; radio frequency ablation; recurrence

摘要："ObjectiveTo analyze the effect of depression on the recurrence of atrial fibrillation (AF) 1 year after radio-frequency ablation. MethodsA total of 91 patients with AF admitted to our hospital from January 2020 to July 2021 were studied. All patients were followed up 1 year after radio-frequency ablation. A total of 91 subjects were divided into recurrence group (n = 30) and no recurrence group (n = 61) according to the recurrence situation 1 year after radio-frequency ablation. Age, disease course, body mass index (BMI), gender, echocardiography (left atrial diameter), blood inflammatory indicators (neutrophil count, lymphocyte count, and monocyte count), and Self-rating Depression Scale (SDS) scores were compared between the two groups. Logistic multivariate regression analysis was used to analyze the effect of SDS score and other indexes on the recurrence of AF 1 year after radio-frequency ablation. ResultsThe age of patients in relapse group was higher than that in no relapse group (P < 0.05) and the course of disease was longer than that of the no recurrence group (P < 0.05). The BMI was higher than that of the no recurrence group (P < 0.05) and the left atrial diameter was greater than that of the no recurrence group (P < 0.05). Neutrophil count and monocyte count were significantly higher than those in no recurrence group (P < 0.05) and the lymphocyte count was significantly lower than that in the no recurrence group (P < 0.05). There were significant differences in SDS score composition between the two groups (P < 0.05) and the composition ratio of patients with moderate and major depression in the relapsing group was significantly higher than that in the non-relapsing group. The composition ratio of patients without depression in the relapsing group was significantly lower than that in the non-relapsing group. Multivariate analysis showed that age, disease course, BMI, left atrial diameter, neutrophil count, lymphocyte count, monocyte count, and SDS score were all independent factors affecting the recurrence of AF patients 1 year after radio frequency ablation (P < 0.05). Compared with patients without depression, patients with mild, moderate and major depression had an increased risk of recurrence by 74.0, 98.2, and 151.2% 1 year after radio-frequency ablation, respectively (OR = 1.740, 1.982, and 2.512). ConclusionThere is a high rate of depression in patients with AF. Depression is an important factor affecting the early recurrence of patients with AF after radio-frequency ablation."

基金机构：Research Project of Anhui Provincial Health Commission; Fuyang City Science and Technology Bureau of Science and Technology Plan Project; [AHWJ2021b070]; [FK202081001]

基金资助正文：Funding This study was supported by the Research Project of Anhui Provincial Health Commission (AHWJ2021b070) and Fuyang City Science and Technology Bureau of Science and Technology Plan Project (FK202081001).