The effect of bone defect size on the 3D accuracy of alveolar bone augmentation performed with additively manufactured patient-specific titanium mesh

作者全名："Yang, Wei; Chen, Dan; Wang, Chao; Apicella, Davide; Apicella, Antonio; Huang, Yuanding; Li, Linzhi; Zheng, Lingling; Ji, Ping; Wang, Lizhen; Fan, Yubo"

作者地址："[Yang, Wei; Wang, Chao; Huang, Yuanding; Li, Linzhi; Ji, Ping] Chongqing Med Univ, Stomatol Hosp, Chongqing 401147, Peoples R China; [Yang, Wei; Huang, Yuanding; Li, Linzhi; Ji, Ping] Chongqing Municipal Key Lab Oral Biomed Engn, Oral Higher Educ Biomed Engn, Chongqing 401147, Peoples R China; [Yang, Wei; Huang, Yuanding; Li, Linzhi; Ji, Ping] Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing 401147, Peoples R China; [Chen, Dan; Wang, Chao; Zheng, Lingling; Wang, Lizhen; Fan, Yubo] Beihang Univ, Beijing Adv Innovat Ctr Biomed Engn, Sch Biol Sci & Med Engn, Sch Engn Med,Key Lab Biomech & Mechanobiol,Minist, Beijing 100083, Peoples R China; [Apicella, Davide] calabrodental Hosp, Marrelly Hlth, I-88900 Crotone, Italy; [Apicella, Antonio] Univ Campania, Dept Architecture & Ind Design, Adv Mat Lab, I-81031 Aversa, Italy"

通信作者："Wang, C (通讯作者)，Chongqing Med Univ, Stomatol Hosp, Chongqing 401147, Peoples R China.; Wang, C (通讯作者)，Beihang Univ, Beijing Adv Innovat Ctr Biomed Engn, Sch Biol Sci & Med Engn, Sch Engn Med,Key Lab Biomech & Mechanobiol,Minist, Beijing 100083, Peoples R China."

来源：BMC ORAL HEALTH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000915107800006

JCR分区：Q2

影响因子：2.9

年份：2022

卷号：22

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Alveolar bone defects; Additively manufactured patient-specific titanium mesh; Bone augmentation; Digital registration; CAD/CAM

摘要："Objective: Additively manufactured (3D-printed) titanium meshes have been adopted in the dental field as nonresorbable membranes for guided bone regeneration (GBR) surgery. However, according to previous studies, inaccuracies between planned and created bone volume and contour are common, and many reasons have been speculated to affect its accuracy. The size of the alveolar bone defect can significantly increase patient-specific titanium mesh design and surgical difficulty. Therefore, this study aimed to analyze and investigate the effect of bone defect size on the 3D accuracy of alveolar bone augmentation performed with additively manufactured patient-specific titanium meshes. Methods: Twenty 3D-printed patient-specific titanium mesh GBR surgery cases were enrolled, in which 10 cases were minor bone defect/augmentation (the planned bone augmentation surface area is less than or equal to 150 mm(2) or one tooth missing or two adjacent front-teeth/premolars missing) and another 10 cases were significant bone defect/augmentation (the planned bone augmentation surface area is greater than 150 mm(2) or missing adjacent teeth are more than two (i.e. >= three teeth) or missing adjacent molars are >= two teeth). 3D digital reconstruction/superposition technology was employed to investigate the bone augmentation accuracy of 3D-printed patient specific titanium meshes. Results: There was no significant difference in the 3D deviation distance of bone augmentation between the minor bone defect/augmentation group and the major one. The contour lines of planned-CAD models in two groups were basically consistent with the contour lines after GBR surgery, and both covered the preoperative contour lines. Moreover, the exposure rate of titanium mesh in the minor bone defect/augmentation group was slightly lower than the major one. Conclusion: It can be concluded that the size of the bone defect has no significant effect on the 3D accuracy of alveolar bone augmentation performed with the additively manufactured patient-specific titanium mesh."

基金机构："National Natural Science Foundation of China [11872135, 12072055, 12172034, U20A20390]; Natural Science Foundation of Beijing [L212063]; Fundamental Research Funds for the Central Universities"

基金资助正文："This work was supported by the National Natural Science Foundation of China (Grant No. 11872135, 12072055, 12172034, U20A20390), the Natural Science Foundation of Beijing (Grant No. L212063) and the Fundamental Research Funds for the Central Universities"