Hematological parameters in patients with acnes

作者全名："Chen, Tingqiao; Chen, Yangmei; Shao, Xinyi; Chen, Jiayi; Liu, Lin; Li, Yuxin; Pu, Yihuan; Chen, Jin"

作者地址："[Chen, Tingqiao; Chen, Yangmei; Shao, Xinyi; Chen, Jiayi; Liu, Lin; Li, Yuxin; Pu, Yihuan; Chen, Jin] Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, Chongqing, Peoples R China; [Chen, Jin] Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Chen, J (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：JOURNAL OF COSMETIC DERMATOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000931305300001

JCR分区：Q2

影响因子：2.3

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：acne vulgaris; derived neutrophil-to-lymphocyte ratio; inflammatory factors; lymphocyte to monocyte ratio; systemic immune-inflammation index

摘要："ObjectiveTo compare complete blood count (CBC) parameters and inflammatory factors in the patients with different grade of acne vulgaris and healthy controls. MethodsA total of 20 patients were enrolled in this study. Patients were divided into mild group and moderate-to-severe group based on the acne severity, and compared to controls. Inflammatory factors (TNF-alpha, IL-6, IL-8, and IL1-alpha) detected by ELISA and complete blood count parameters (MPV, NLR, dNLR, PLR, LMR, and SII) obtained by routine blood tests were compared among the three group. ResultsAll CBC parameters were not significantly elevated in patients with acne compared to healthy controls. However, the present studies have found that the inflammatory factors in acne patients were significantly elevated relative to healthy controls, and increase with the acne grade. ConclusionsInflammatory factors are convenient parameters to show inflammatory response to acne vulgaris, and may be a new clinical method for judging the acne grades of objectively. Considering the use of antibiotic, we believe that this metric worth further study."

基金机构：National Natural Science Foundation of China [n82073462]

基金资助正文："National Natural Science Foundation of China, Grant/Award Number: n82073462"