Efficacy and safety of erector spinae plane block for postoperative analgesia in breast cancer surgery-A systematic review and meta-analysis

作者全名："Guan, Hong-Yu; Yuan, Yi; Gao, Kai; Luo, Hong-Xia"

作者地址："[Guan, Hong-Yu; Yuan, Yi; Luo, Hong-Xia] Chongqing Med Univ, Yongchuan Hosp, Dept Anesthesiol, Chongqing, Peoples R China; [Gao, Kai] Cent South Univ, Xiangya Hosp 3, Dept Anesthesiol, Changsha, Peoples R China; [Guan, Hong-Yu] Chongqing Med Univ, Yongchuan Hosp, Dept Anesthesiol, Chongqing 402160, Peoples R China"

通信作者："Guan, HY (通讯作者)，Chongqing Med Univ, Yongchuan Hosp, Dept Anesthesiol, Chongqing 402160, Peoples R China."

来源：JOURNAL OF SURGICAL ONCOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000939428800001

JCR分区：Q2

影响因子：2

年份：2023

卷号：127

期号：6

开始页：905

结束页：920

文献类型：Review

关键词：breast surgery; ESPB; opioid consumption; pain scores; postoperative analgesia

摘要："Background and ObjectivesWe aim to evaluate the analgesic efficacy and safety of erector spinae plane block (ESPB) for postoperative analgesia in breast cancer surgeries. MethodsPubMed, Web of Science, CBM, Embase, Cochrane, Wanfang, VIPP, and CNKI were searched to identify published eligible randomized controlled trials. The primary results were the postoperative 24 h morphine consumption and pain scores, while the secondary outcomes included pain scores at other times, press times of patient-controlled intravenous analgesia (PCIA), times to request for first rescue analgesia, the incidence of request for rescue analgesia, opioid-related complications, nerve blocks related complications and patient satisfaction. ResultsWe included 20 studies meeting the inclusion criteria, which involved 1293 participants. The morphine consumption and the pain scores during 24 h postoperatively were significantly decreased in the ESPB group versus the control group (p < 0.00001). Furthermore, ESPB also reduced pain scores at other time points, press times of PCIA, and times to first rescue analgesia requirement. Meanwhile, there was a lower incidence of postoperative nausea and vomiting, and skin pruritus in the ESPB group than in the control group. ConclusionsCompared to general anesthesia alone, ESPB combined with general anesthesia can effectively reduce the postoperative pain intensity within 48 h and opioid consumption within 24 h after breast cancer surgery, and reduce the incidence of opioid and nerve blocks related complications."

基金机构：　

基金资助正文：