Melanocyte stem cells and hair graying

作者全名："Zhang, Xiaojiao; Zhu, Jinyu; Zhang, Jiezhi; Zhao, Hengguang"

作者地址："[Zhang, Xiaojiao; Zhu, Jinyu] Chongqing Med Univ, Univ Town Hosp, Dept Dermatol, Chongqing, Peoples R China; [Zhang, Jiezhi; Zhao, Hengguang] Chongqing Med Univ, Affiliated Hosp 2, Dept Dermatol, Chongqing, Peoples R China"

通信作者："Zhao, HG (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Dermatol, Chongqing, Peoples R China."

来源：JOURNAL OF COSMETIC DERMATOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000940538700001

JCR分区：Q2

影响因子：2.3

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Review; Early Access

关键词：ectopic differentiation of melanocyte stem cells; hair graying; melanocyte; melanocyte stem cells

摘要："ObjectivesTo explore the relationship between melanocyte stem cells in the hair follicle bulge and hair graying so as to fully understand their key role in the pathogenesis of hair graying. MethodsThe published articles about ""hair graying, hair color, pigmentation disorders"" and ""melanocyte stem cells, melanocyte"" were searched and analyzed in PubMed to explore their relationship. ResultsMelanocytes in hair bulb are involved in the pathogenesis of hair graying as well as the melanocyte stem cells in hair follicle bulge also play important roles in the formation of hair graying through some ways. ConclusionLoss of melanocyte stem cells in hair follicle bulge is one of the main reasons of hair graying, and more researches are needed to explain the underlying mechanisms of ectopic differentiation of melanocyte stem cells in different individual."

基金机构：Hengguang Zhao [82173440]

基金资助正文："Hengguang Zhao, Grant/Award Number: the National Natural Science Foundation of China (No.82173440)"