Changes in emotion-related EEG components and brain lateralization response to negative emotions in adolescents with nonsuicidal self-injury: An ERP study

作者全名："Zhao, Lin; Zhou, Dongdong; Ma, Lingli; Hu, Jinhui; Chen, Ran; He, Xiaoqing; Peng, Xinyu; Jiang, Zhenghao; Ran, Liuyi; Xiang, Jiaojiao; Zeng, Qi; Zhou, Yi; Dai, Linxi; Zhang, Qi; Hong, Su; Wang, Wo; Kuang, Li"

作者地址："[Zhao, Lin; Ma, Lingli; Peng, Xinyu; Xiang, Jiaojiao; Zhou, Yi; Dai, Linxi; Zhang, Qi; Hong, Su; Kuang, Li] Chongqing Med Univ, Affiliated Hosp 1, Dept Psychiat, Chongqing 400016, Peoples R China; [Zhou, Dongdong; Hu, Jinhui; Chen, Ran; He, Xiaoqing; Jiang, Zhenghao; Ran, Liuyi; Zeng, Qi; Wang, Wo] Chongqing Med Univ, Univ Town Hosp, Mental Hlth Ctr, Chongqing, Peoples R China"

通信作者："Kuang, L (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Psychiat, Chongqing 400016, Peoples R China."

来源：BEHAVIOURAL BRAIN RESEARCH

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:000950622300001

JCR分区：Q2

影响因子：2.6

年份：2023

卷号：445

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Nonsuicidal self-injury; Adolescents; Negative emotion; Emotional processing; Inhibitory control; Brain lateralization effect

摘要："Nonsuicidal self-injury (NSSI) is a serious risk behavior in adolescents and is a high risk factor for suicide, while negative emotions can lead to increased NSSI behaviors. In this study, we investigated the altered behavioral performance and neural reactivity of adolescents with NSSI by using a two-choice oddball paradigm when exposed to negative emotional stimuli, and analyzed the brain lateralization effect. Our data indicated that adolescents with NSSI exhibit more pronounced N250, P300, and LPP components during negative emotional face stimulation, as evidenced by a smaller N250 wave amplitude, larger P300 wave amplitude, steeper LPP waveform, and faster fallback baseline; and the presence of brain lateralization responses in both the N250 component and the LPP component. These results suggested that adolescents with NSSI showed significant al-terations in cognitive EEG components associated with emotional processing during negative emotional face stimulation, particularly in EEG components representing inhibitory control, and there was a lateralization effect on emotional processing in the brain, with different processing stages and different dominance of the left and right brain."

基金机构：National Natural Science Foundation of China (NSFC) [81971286]; Natural Science Foundation of Chongqing [cstc2020jcyj-msxmX0222]; Science and Technology Bureau of Chongqing [CSTC2021jscx- gksb-N0002]

基金资助正文：Funding Funding for this study was provided by a grant (81971286) from the National Natural Science Foundation of China (NSFC) . And this study was also supported by a grant (cstc2020jcyj-msxmX0222) from the Natural Science Foundation of Chongqing and a grant (CSTC2021jscx- gksb-N0002) from the Science and Technology Bureau of Chongqing.