"Interaction of Harmful Alcohol Use and Tea Consumption on Hyperuricemia Among Han Residents Aged 30-79 in Chongqing, China"

作者全名："Ding, Xianbin; Chen, Liling; Tang, Wenge; Chen, Ting; Xu, Jingru; Yang, Xianxian; Ding, Rui; Tang, Xiaojun"

作者地址："[Ding, Xianbin; Chen, Liling; Tang, Wenge; Chen, Ting; Xu, Jingru; Yang, Xianxian] Chongqing Municipal Ctr Dis Control & Prevent, Chongqing, Peoples R China; [Ding, Rui] Chongqing Med Univ, Med Coll 1, Chongqing, Peoples R China; [Tang, Xiaojun] Chongqing Med Univ, Med & Social Dev Res Ctr, Sch Publ Hlth & Management, Chongqing, Peoples R China"

通信作者："Chen, LL (通讯作者)，Chongqing Municipal Ctr Dis Control & Prevent, Chongqing, Peoples R China."

来源：INTERNATIONAL JOURNAL OF GENERAL MEDICINE

ESI学科分类：　

WOS号：WOS:000951494400001

JCR分区：Q2

影响因子：2.1

年份：2023

卷号：16

期号：　

开始页：973

结束页：981

文献类型：Article

关键词：hyperuricemia; tea consumption; harmful alcohol use; interaction; Han residents

摘要："Objective: The prevalence of hyperuricemia appears to be high worldwide. We aimed to explore the interaction between harmful alcohol use and tea consumption on hyperuricemia. Methods: This study recruited 22,449 Han residents based on the data from the China Multi-Ethnic Cohort (CMEC) study, Chongqing province, to have a face-to-face electronic questionnaire, physical examination, and clinical laboratory tests. The difference in hyperuricemia between the different populations was compared by the Chi-square test. The interaction between harmful alcohol use and tea consumption was analyzed by the multivariate logistic regression model. Results: Amongst 22,449 participants, the mean age was 51.5 +/- 11.8 years, and 46.83% of them were males. The proportion of harmful alcohol use, tea consumption, and harmful alcohol use and tea consumption were 14.01%, 21.01%, and 6.54%, respectively. Multivariate logistic regression showed that the odds ratio (OR) of harmful alcohol use and tea consumption (OR=2.21, 95% CI: 1.58-3.10) was greater than that of harmful alcohol use (OR=1.63, 95% CI:1.17-2.27) and tea consumption (OR=1.34, 95% CI:1.10- 1.63). Among males, the results were similar (harmful alcohol use and tea consumption: OR=2.02, 95% CI: 1.43-2.84; harmful alcohol use: OR=1.61, 95% CI: 1.14-2.27; tea consumption: OR=1.28, 95% CI: 1.05-1.57). However, among females, the odds ratio of harmful alcohol use and tea consumption (OR=15.50, 95% CI: 1.36-176.50) was more than 10 times than that of only harmful alcohol use (OR=1.55, 95% CI: 0.42-5.69) or tea consumption (OR=1.22, 95% CI: 0.52-2.82). Conclusion: The interaction of harmful alcohol use and tea consumption was a positive risk for hyperuricemia in Han residents aged 30-79 years in China."

基金机构：National Key R&D Program of China [2017YFC0907303]

基金资助正文：Funding This work was supported by the National Key R&D Program of China (grant number: 2017YFC0907303) .