Enhanced effect of a novel bioactive glass-ceramic for dental application

作者全名："Qiu, Lin; Lu, Yu; Dong, Haide; Zhang, Huan; Zhang, Min; Deng, Quanfu; Song, Jinlin"

作者地址："[Qiu, Lin; Lu, Yu; Dong, Haide; Zhang, Huan; Zhang, Min; Deng, Quanfu] Dencare Chongqing Oral Care Co Ltd, Chongqing, Peoples R China; [Qiu, Lin; Song, Jinlin] Chongqing Med Univ, Coll Stomatol, Chongqing, Peoples R China; [Song, Jinlin] Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing, Peoples R China; [Song, Jinlin] Chongqing Municipal Key Lab Oral Biomed Engn Highe, Chongqing, Peoples R China"

通信作者："Qiu, L; Deng, QF (通讯作者)，Dencare Chongqing Oral Care Co Ltd, Chongqing, Peoples R China.; Qiu, L; Song, JL (通讯作者)，Chongqing Med Univ, Coll Stomatol, Chongqing, Peoples R China.; Song, JL (通讯作者)，Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing, Peoples R China.; Song, JL (通讯作者)，Chongqing Municipal Key Lab Oral Biomed Engn Highe, Chongqing, Peoples R China."

来源：CLINICAL ORAL INVESTIGATIONS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000952491600002

JCR分区：Q1

影响因子：3.1

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：Bioactive; Demineralization; Remineralization; Enamel; Dental

摘要："ObjectivesDental caries is the most common chronic disease in humans, caused by the acid produced by the microflora in the mouth that dissolves the enamel minerals. Bioactive glass (BAG) has been used in various clinical applications due to its unique bioactive properties, such as bone graft substitutes and dental restorative composites. In this study, we introduce a novel bioactive glass-ceramic (NBGC) prepared through a sol-gel process under a water-free condition.Materials and methodsThe anti-demineralization and remineralization effects of NBGC were evaluated by comparing the measurements of bovine enamel surface morphology, surface roughness, surface micro-hardness, enamel elements, and mineral content before and after related treatments with a commercial BAG. The antibacterial effect was characterized by minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC).ResultsResults showed that NBGC had greater acid resistance and remineralization potential compared to commercial BAG. The fast formation of a hydroxy carbonate apatite (HCA) layer suggests efficient bioactivity."

基金机构：　

基金资助正文：