Effects of COVID-19 home quarantine on pregnancy outcomes of patients with gestational diabetes mellitus: a retrospective cohort study

作者全名："Cai, Qin-Yu; Yang, Yin; Ruan, Ling-Ling; Wang, Dang-Dang; Cui, Han-Lin; Yang, Shu; Liu, Wen-Jie; Luo, Xin; Liu, Tai-Hang"

作者地址："[Cai, Qin-Yu; Wang, Dang-Dang; Liu, Wen-Jie; Liu, Tai-Hang] Chongqing Med Univ, Sch Basic Med Sci, Dept Bioinformat, Chongqing, Peoples R China; [Yang, Yin] Chongqing Med Univ, Dept Infect Controlling Sect, Women & Childrens Hosp, Chongqing, Peoples R China; [Ruan, Ling-Ling; Wang, Dang-Dang; Cui, Han-Lin; Yang, Shu; Luo, Xin; Liu, Tai-Hang] Chongqing Med Univ, Joint Int Res Lab Reprod & Dev, Minist Educ, Chongqing, Peoples R China; [Luo, Xin] Chongqing Med Univ, Affiliated Hosp 1, Dept Obstet, Chongqing, Peoples R China; [Luo, Xin; Liu, Tai-Hang] Chongqing Med Univ, Box 197,1 Yixueyuan Rd, Chongqing 400016, Peoples R China"

通信作者："Luo, X; Liu, TH (通讯作者)，Chongqing Med Univ, Box 197,1 Yixueyuan Rd, Chongqing 400016, Peoples R China."

来源：JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000956092200001

JCR分区：Q3

影响因子：1.7

年份：2023

卷号：36

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：COVID-19; home quarantine; pregnancy outcomes; GDM; macrosomia

摘要："Objective This study aimed to evaluate the effects of the home quarantine on pregnancy outcomes of gestational diabetes mellitus (GDM) patients during the COVID-19 outbreak. Methods The complete electronic medical records of patients with GDM with home quarantine history were collected and classified into the home quarantine group from 24 February 2020 to 24 November 2020. The same period of patients with GDM without home quarantine history were included in the control group from 2018 to 2019. The pregnant outcomes of the home quarantine and control groups were systematically compared, such as neonatal weight, head circumference, body length, one-minute Apgar score, fetal macrosomia, and pre-term delivery. Results A total of 1358 patients with GDM were included in the analysis, including 484 in 2018, 468 in 2019, and 406 in 2020. Patients with GDM with home quarantine in 2020 had higher glycemic levels and adverse pregnancy outcomes than in 2018 and 2019, including higher cesarean section rates, lower Apgar scores, and higher incidence of macrosomia and umbilical cord around the neck. More importantly, the second trimester of home quarantine had brought a broader impact on pregnant women and fetuses. Conclusion Home quarantine has aggravated the condition of GDM pregnant women and brought more adverse pregnancy outcomes during the COVID-19 outbreak. Therefore, we suggested governments and hospitals strengthen lifestyle guidance, glucose management, and antenatal care for patients with GDM with home quarantine during public health emergencies."

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