Pregnancy outcomes following ultrasound-guided high-intensity focused ultrasound in submucous leiomyomas: a retrospective study

作者全名："Qu, Dacheng; Liu, Yue; Jiang, Jing; Shi, Qiuling; Zhou, Honggui; Wang, Zhibiao"

作者地址："[Qu, Dacheng; Shi, Qiuling; Wang, Zhibiao] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China; [Qu, Dacheng; Wang, Zhibiao] Chongqing Med Univ, Chongqing Key Lab Biomed Engn, Chongqing, Peoples R China; [Qu, Dacheng; Liu, Yue; Jiang, Jing; Zhou, Honggui] North Sichuan Med Coll, Dept Obstet & Gynecol, Affiliated Hosp, Nanchong, Peoples R China; [Qu, Dacheng; Zhou, Honggui] North Sichuan Med Coll, Noninvas & Microinvas Lab Gynecol, Affiliated Hosp, Nanchong, Peoples R China; [Shi, Qiuling] Chongqing Med Univ, Sch Publ Hlth, Chongqing, Peoples R China; [Zhou, Honggui] North Sichuan Med Coll, Dept Obstet & Gynecol, Noninvas & Microinvas Lab Gynecol, Affiliated Hosp, Nanchong 637000, Peoples R China; [Wang, Zhibiao] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing Key Lab Biomed Engn, Chongqing 400016, Peoples R China"

通信作者："Zhou, HG (通讯作者)，North Sichuan Med Coll, Dept Obstet & Gynecol, Noninvas & Microinvas Lab Gynecol, Affiliated Hosp, Nanchong 637000, Peoples R China.; Wang, ZB (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing Key Lab Biomed Engn, Chongqing 400016, Peoples R China."

来源：INTERNATIONAL JOURNAL OF HYPERTHERMIA

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000956755700001

JCR分区：Q2

影响因子：3

年份：2023

卷号：40

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Submucous leiomyomas; effective volume in the uterus cavity; ultrasound-guided high-intensity focused ultrasound; pregnancy; delivery

摘要："Objective To investigate the impact of ultrasound-guided high-intensity focused ultrasound (USgHIFU) on pregnancy in submucous leiomyomas. Materials and methods Between October 2015 and October 2021, a retrospective observational study was conducted at the Affiliated Hospital of North Sichuan Medical College, China, for 32 women with submucous leiomyomas who became pregnant after USgHIFU. Pregnancy outcomes, submucous leiomyomas characteristics, and USgHIFU parameters were analyzed. Results A total of 17 (53.1%) deliveries were successfully achieved, with full-term delivery in 16 (94.1%) patients and preterm delivery in 1 (5.9%). After USgHIFU, the effective volume in the uterus cavity and the volume of submucous leiomyomas shrank in all 32 patients. The median time to achieve pregnancy after USgHIFU was 11.0 months. Before pregnancy, myoma type was downgraded in 13 (40.6%) patients, stable in 10 (31.3%) and upgraded in 9 (28.1%). The vaginal expulsion rate of submucous leiomyomas was 28.1%, with complete expulsion in 3 (9.4%) patients and partial expulsion in 6 (18.8%). After USgHIFU, the size of submucous leiomyomas did not increase in each trimester (all p > 0.05). The high complications rate during pregnancy (7/17, 41.2%) was associated with advanced maternal age, with only one (5.9%) premature rupture of membranes possibly associated with submucous leiomyomas. There were 6 (35.5%) vaginal delivery and 11 (64.7%) cesarean sections. All 17 newborns developed well, with a mean birth weight of 3482 g. Conclusions In patients with submucous leiomyomas, pregnancies and full-term deliveries can be successfully achieved following USgHIFU, with few related complications."

基金机构：Bureau of Science and Technology Nanchong City [19SXHZ0338]; North Sichuan Medical College [2021LC005]

基金资助正文：The work was supported by the Bureau of Science and Technology Nanchong City under Grant [19SXHZ0338] and Affiliated Hospital of North Sichuan Medical College [2021LC005].