A pilot study on intracerebral hemorrhage imaging based on electrical capacitance tomography

作者全名："Xu, Rui; Zhuang, Wei; Bai, Zelin; Wang, Feng; Chen, Mingsheng; Liu, Nan; Jin, Gui"

作者地址："[Xu, Rui] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurosurg, Chongqing, Peoples R China; [Zhuang, Wei; Bai, Zelin; Wang, Feng; Chen, Mingsheng; Jin, Gui] Third Mil Med Univ, Army Med Univ, Coll Biomed Engn, Chongqing, Peoples R China; [Liu, Nan] Chongqing Red Cross Hosp, Jiangbei Dist Peoples Hosp, Dept Radiol, Chongqing, Peoples R China"

通信作者："Jin, G (通讯作者)，Third Mil Med Univ, Army Med Univ, Coll Biomed Engn, Chongqing, Peoples R China.; Liu, N (通讯作者)，Chongqing Red Cross Hosp, Jiangbei Dist Peoples Hosp, Dept Radiol, Chongqing, Peoples R China."

来源：FRONTIERS IN PHYSICS

ESI学科分类：PHYSICS

WOS号：WOS:000964156300001

JCR分区：Q2

影响因子：1.9

年份：2023

卷号：11

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：intracerebral hemorrhage; ECT; image reconstruction; tomography; bleeding

摘要："Introduction: Intracerebral hemorrhage (ICH) is a devastating disease with high rates of mortality and disability. The survival rate and postoperative outcome of ICH can be greatly improved through prompt diagnosis and treatment. CT and MRI are now the gold standards for the diagnosis of ICH, but they are not practical for use in pre-hospital emergencies or at the bedside monitoring.Methods: Based on the earlier research of ICH detection with a single parallel plate electrode sensor, we developed a 16-electrode Electrical Capacitance Tomography (ECT) system for two-dimensional tomographic imaging of ICH in this study. A 5-layer spherical numerical model and an ex vivo porcine physical model of ICH were created for ECT simulation imaging and actual imaging, respectively, to assess the feasibility of this ECT for ICH imaging.Results: The bleeding circles were easily seen in the image reconstruction in numerical imaging. In ex vivo imaging, the existence of bleeding was also more clearly shown with the ECT system; however, the position of the bleeding reconstructed in the image was offset by 3 mm from the real site.Discussion: The study analyzes the causes of this discrepancy and discusses the steps that may be taken to rectify it. Overall, the simulation and ex vivo experimental trials validated the potential of ICH imaging with the ECT method; however, further work is required to increase the performance of the ECT and a more advanced imaging reconstruction algorithm is urgently needed for ICH imaging."

基金机构：Foundation of Scientific and Technological Innovation Capability Promotion of the Army Medical University [2019XQY06]

基金资助正文：Funding This research was funded by the Foundation of Scientific and Technological Innovation Capability Promotion of the Army Medical University (2019XQY06).