The Effects of Carbon Dots from Hordei Fructus Germinatus Carbonisatus on Glycometabolism and alpha-Glycosidase Activity

作者全名："Song, Xingxing; Cao, Peng; Bai, Xue; Zhao, Yusheng; Zhang, Yifan; Kong, Hui; Zhao, Yan; Qu, Huihua"

作者地址："[Song, Xingxing] Chongqing Med Univ, Dept Tradit Chinese Med, Childrens Hosp, Minist Educ,Key Lab Disorders,Natl Clin Res Ctr Ch, Chongqing 100029, Peoples R China; [Cao, Peng] Beijing Univ Chinese Med, Affiliated Hosp 3, Educ Sect, Beijing 100029, Peoples R China; [Bai, Xue; Zhao, Yusheng; Zhang, Yifan; Kong, Hui; Zhao, Yan] Beijing Univ Chinese Med, Sch Basic Med Sci, Beijing 100029, Peoples R China; [Qu, Huihua] Beijing Univ Chinese Med, Ctr Sci Expt, Beijing 100029, Peoples R China"

通信作者："Qu, HH (通讯作者)，Beijing Univ Chinese Med, Ctr Sci Expt, Beijing 100029, Peoples R China."

来源：JOURNAL OF BIOMEDICAL NANOTECHNOLOGY

ESI学科分类：BIOLOGY & BIOCHEMISTRY

WOS号：WOS:000964560500001

JCR分区：Q3

影响因子：2.9

年份：2022

卷号：18

期号：12

开始页：2750

结束页：2758

文献类型：Article

关键词：Carbon Dots; Hordei Fructus Germinatus Carbonisatus; A-glycosidase

摘要："Hordei Fructus Germinatus Carbonisatus (HFC), the carbonized malt known as Maiya-tan in China, has been used as an effective natural treatment to improve digestion for a long time. In this research, we separated and distinguished CDs (carbon dots) from HFC, which were prepared using traditional methods. The HFC CDs had a lattice spacing of 0.26 nm and an average size of 4.3 nm, according to morphology investigations, which revealed that they were nearly spherical. The significant elements in the HFC CDs were C, O, and N. These HFC CDs produced several emissive traps between pi - pi * states because they had functional groups including C-OH, -NH, C=O, and C-H on their surface, according to X-ray photoelectron spectroscopy investigation. Our results indicated that HFC CDs could effectively reduce postprandial blood glucose and inhibit alpha-glycosidase in vitro, which suggested that HFC CDs may affect aspects of carbohydrate metabolism. This work indicates that HFC CDs may have the potential to play a crucial clinical role in regulating blood sugar."

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