"Incidence, Prognostic Factors, and Survival of Patients with Renal Cancer: A Population-Based Study"

作者全名："Zheng, Bai-Shu; Wang, Shun-De; Zhang, Jun-Yong; Ge, Cheng-Guo"

作者地址："[Zheng, Bai-Shu; Zhang, Jun-Yong; Ge, Cheng-Guo] Chongqing Med Univ, Affiliated Hosp 2, Dept Urol, Chongqing, Peoples R China; [Wang, Shun-De] Chen Jiaqiao Hosp Sha Pingba Dist Chongqing City, Dept Urol, Chongqing, Peoples R China"

通信作者："Ge, CG (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Urol, Chongqing, Peoples R China."

来源：JOURNAL OF INVESTIGATIVE SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000965147500001

JCR分区：Q2

影响因子：2.1

年份：2023

卷号：36

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Renal cancer; nomogram; overall survival; prognosis; SEER

摘要："Background The main objective of this article is to understand trends in the incidence of renal cancer and to construct a nomogram to predict the prognosis of patients with renal cancer by analyzing clinical parameters. Methods We extracted data from the Surveillance, Epidemiology and End Results (SEER) database for patients with renal cancer from 2010 to 2015. The incidence rate was calculated to understand the trend of renal cancer in recent years, and the Kaplan-Meier method was used to analyze the relationship between patients' clinical variables and overall survival. Nomogram and calibration curves were constructed based on factors predicted by multivariate Cox regression. Results Data from 68,496 eligible renal cancer patients were included in the study. The incidence of renal cancer was higher in men than women and tended to stabilize over time. We further found that age, gender, marital status, AJCC stage, histological type, metastatic disease, and surgery were independent parameters for prognosis in renal cancer patients. Finally, a nomogram was constructed based on the above parameters, and its validity was verified with the agreement index and calibration curve. Conclusion Renal cancer incidence trend gradually stabilized. Seven independent parameters for renal cancer patients were obtained by analysis and utilized to construct a nomogram that could provide guidance for clinical practice."

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