Predictive factors on postoperative venous thromboembolism after minimally invasive colorectal cancer surgery: a retrospective observational study

作者全名："Wu, Dabin; Gu, Haitao; Tang, Yunhao; Peng, Linglong; Liu, Hang; Jiang, Yahui; Xu, Zhiquan; Wei, Qi; Wang, Yaxu"

作者地址："[Wu, Dabin; Gu, Haitao; Tang, Yunhao; Peng, Linglong; Liu, Hang; Jiang, Yahui; Xu, Zhiquan; Wei, Qi; Wang, Yaxu] Chongqing Med Univ, Dept Gastrointestinal Surg, Affiliated Hosp 2, Chongqing 400010, Peoples R China"

通信作者："Wang, YX (通讯作者)，Chongqing Med Univ, Dept Gastrointestinal Surg, Affiliated Hosp 2, Chongqing 400010, Peoples R China."

来源：BMC SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000967894700004

JCR分区：Q2

影响因子：1.6

年份：2023

卷号：23

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Minimally invasive surgery; Colorectal cancer; Venous thromboembolism; Predictive factors

摘要："BackgroundVenous thromboembolism (VTE) is a serious and preventable postoperative complication. However, the predictive significance of perioperative biochemical parameters for VTE after minimally invasive colorectal cancer surgery remains unclear.MethodsA total of 149 patients undergoing minimally invasive colorectal cancer surgery were collected between October 2021 and October 2022. Biochemical parameters related to preoperative and postoperative day 1, day 3, and day 5 were collected, including D-Dimer, mean platelet volume (MPV), and maximum amplitude (MA) of thromboelastography (TEG). Receiver operating characteristic (ROC) curves were used to explore the predictive powers of meaningful biochemical parameters for postoperative VTE, and calibration curves were used to assess predictive accuracy.ResultsThe overall cumulative incidence of VTE was 8.1% (12/149). The preoperative and postoperative day 3 D-Dimer, postoperative day 3, and day 5 MPV, and postoperative day 1, day 3, and day 5 TEG-MA was significantly higher in the VTE group than in the non-VTE group (P < 0.05). The results of both the ROC curve and the calibration curve indicated that these meaningful D-Dimer, MPV, and TEG-MA had moderate discrimination and consistency for postoperative VTE.ConclusionsD-Dimer, MPV, and TEG-MA may predict postoperative VTE in patients undergoing minimally invasive surgery for colorectal cancer at specific times in the perioperative period."

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