Endoscopic Transsphenoidal Surgery with a Layered Peel Strategy for Cushing's Disease Treatment: A Case Series

作者全名："Shao, Chuan; Wang, Junwei; Wang, Pan; Wu, Nan"

作者地址："[Shao, Chuan; Wang, Junwei; Wang, Pan; Wu, Nan] Chongqing Gen Hosp, Dept Neurosurg, Chongqing 401147, Peoples R China; [Shao, Chuan; Wu, Nan] Chongqing Med Univ, Grad Inst, Chongqing 400016, Peoples R China"

通信作者："Wu, N (通讯作者)，Chongqing Gen Hosp, Dept Neurosurg, Chongqing 401147, Peoples R China.; Wu, N (通讯作者)，Chongqing Med Univ, Grad Inst, Chongqing 400016, Peoples R China."

来源：BRAIN SCIENCES

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:000977493800001

JCR分区：Q3

影响因子：2.7

年份：2023

卷号：13

期号：4

开始页：　

结束页：　

文献类型：Article

关键词：Cushing's disease; endoscopic transsphenoidal surgery; outcomes; pituitary adenoma

摘要："Patients with Cushing's disease (CD) who underwent endoscopic transsphenoidal surgery (ETS) with a layered peel strategy at our center were retrospectively analyzed. Records on patients' basic characteristics, preoperative and early postoperative evaluations, perioperative complications, and follow-up were collected. A total of 12 unselected, consecutive patients with CD were identified. Ten of the twelve patients were female. All tumors were confirmed by magnetic resonance imaging, with a maximum tumor diameter ranging from 5 mm to 11 mm. A lower rate of surgical complications was identified postoperatively, with no cases of carotid artery injury, epistaxis, hematoma, visual disturbance, or intracranial infection, but with one case of cerebrospinal fluid rhinorrhea. Ten patients experienced immediate remission, and two had delayed remission. No recurrence events were observed during a median follow-up of 51 months. In conclusion, our preliminary experience indicated that ETS with a layered peel strategy provided a perfect remission rate, low complication rate, and no recurrence in a case series of CD patients. Given the limited number of cases, future studies are warranted to confirm its effectiveness and safety."

基金机构：　

基金资助正文：